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Figure 2 | BMC Nephrology

Figure 2

From: Tyrosine kinases inhibition by Imatinib slows progression in chronic anti-thy1 glomerulosclerosis of the rat

Figure 2

Renal histology 20 weeks after induction of chronic anti-thy1 glomerulosclerosis (cGS). Administration of Imatinib was started 7 days after injection of anti-thy1 antibody into uni-nephrectomized rats (cGS + Imatinib). Nonnephritic animals with (1-K Control) and without uninephrectomy (2-K Control) received an injection with similar volumes of PBS. Shown are characteristic periodic acid-schiff (PAS)-stained renal sections from a normal control animal (A), an animal with uninephrectomie (B), an animal with anti-thy1-induced cGS without (C) and with Imatinib (D) treatment. Magnification ×400.

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