Cultured murine eEOCs and renal function after cell therapy. A depicts BS 1+/acLDL+ cells (eEOCs) (green: BS 1 lectin-FITC, red: acLDL-Dil, blue: nuclei, magnification × 100). Eighty-six ± 3.7% of all cultured cells showed double-positive staining. B shows renal function of cell injected animals. Administration of untreated eEOCs did not improve renal function but injection of Ang-1 pretreated cells significantly improved renal function as compared to mice without cell therapy and to mice with administration of untreated eEOCs. C (C.1 and C.2) shows immunofluorescence images from kidneys of cell-injected mice. Since previous investigations showed eEOC accumulation in the medullo-papillary area, our particular interest focused on the borderzone between medulla and papilla. Nevertheless, cell were de facto absent in both groups (untreated cells – C.1 and Ang-1 pretreated cells – C.2) (magnification in C × 40, IRI: ischemia reperfusion injury, Data as mean ± SEM, *: p < 0.05).