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Table 1 Characteristics of chronic renal insufficiency cohort participants with high sensitivity troponin t measurements

From: Predictors of high sensitivity cardiac troponin T in chronic kidney disease patients: a cross-sectional study in the chronic renal insufficiency cohort (CRIC)

 

Undetectable

Tertile I

Tertile II

Tertile III

P

 

(hs-TnT < 3)

(3.00-8.63)

(8.67-17.03)

(17.05-738.7)

 
 

(n=474)

(n=666)

(n=661)

(n=663)

 

Hs-TnT (pg/ml)*

1.5 (1.5-1.5)

5.7 (4.6-7.1)

11.9 (10.1-14.2)

30.0 (21.4-45.3)

< 0.001

Age

51.5 (11.8)

55.7 (11.8)

60.3 (10.7)

59.2 (11.1)

< 0.001

Female

75.5

53.8

42.7

29.1

< 0.001

Race

    

< 0.001

Non-Hispanic White

53.2

49.9

45.1

29.1

 

Non-Hispanic Black

33.8

35.6

38.0

45.4

 

Hispanic

8.4

9.0

13.9

21.4

 

Other

4.6

5.6

3.0

4.1

 

Diabetes

14.8

29.1

45.1

68.3

< 0.001

Hypertension

68.6

82.1

91.4

94.7

< 0.001

Current smoking

13.1

10.4

11.8

11.0

0.526

SBP (mmHg) †

124.1 (16.9)

128.3 (17.3)

132.9 (19.5)

140.5 (20.9)

< 0.001

DBP (mmHg) ‡

75.1 (12.1)

75.5 (11.9)

74.3 (12.0)

76.8 (11.8)

0.010

BMI (kg/m 2 ) §

30.6 (8.5)

31.2 (7.9)

32.3 (8.1)

32.5 (7.5)

< 0.001

HDL (mg/dL) ||

54.1 (17.7)

50.9 (15.2)

49.1 (16.2)

46.4 (15.4)

< 0.001

LDL (mg/dL)

108.9 (30.4)

107.7 (34.1)

102.4 (34.7)

98.7 (36.3)

< 0.001

Triglycerides (mg/dL)

144.2 (114.1)

155.2 (115.1)

149.3 (91.1)

161.3 (108.0)

< 0.001

Total cholesterol (mg/dL)

193.7 (37.6)

192.3 (41.4)

184.3 (44.8)

182.0 (45.6)

< 0.001

Serum albumin (g/dL)

4.2 (0.4)

4.1 (0.4)

4.1 (0.4)

3.9 (0.5)

< 0.001

hsCRP (mg/L) #

4.9 (8.3)

4.9 (8.8)

5.4 (8.7)

5.7 (9.8)

0.015

Hemoglobin (g/dL)

13.2 (1.5)

13.2 (1.8)

13.0 (1.8)

12.2 (1.8)

< 0.001

Phosphate (mg/dL)

3.6 (0.6)

3.6 (0.5)

3.6 (0.6)

3.9 (0.7)

< 0.001

FGF-23 (RU/ml)**

104.7 (73.8-160.2)

114.6 (81.3-182.5)

137.4 (93.3-208.8)

171.7 (113.9-293.0)

< 0.001

eGFRcys †† (ml/min/1.73 m 2 )

66.1 (22.7)

55.9 (19.7)

49.5 (16.3)

40.9 (16.2)

< 0.001

ACR (μg/mg) ψ

11.2 (5.0-86.9)

21.3 (5.4-201.7)

30.5 (7.9-279.7)

289.7 (31.4-1393.2)

< 0.001

LV mass (g/m 2.7 ) Ω

43.8 (10.2)

46.1 (10.4)

50.3 (12.8)

55.4 (13.8)

< 0.001

Ejection fraction (%)

55.7 (6.3)

55.9 (6.4)

55.8 (7.4)

54.3 (7.3)

< 0.001

  1. Mean (SD) or median (IQR) are reported for continuous variables and percentage for categorical variables. P values are obtained using ANOVA or Kruskal-Wallis tests for continuous variables and Chi-squared tests for categorical variables. * High sensitivity troponin T. † Systolic blood pressure. ‡ Diastolic blood pressure. § Body mass index. || High density lipoprotein. Low density lipoprotein. # High sensitivity c-reactive protein. ** Fibroblast growth factor 23. †† Cystatin-based estimated glomerular filtration rate. ψ Albumin to creatinine ratio. Ω Left ventricular.