|  | Unadjusted | Model 1 | Model 2 | |||
---|---|---|---|---|---|---|---|
 | N* | Tobit ratio (95% CI) | P | Tobit ratio (95% CI) | P | Tobit ratio (95% CI) | P |
eGFRcys* (ml/min/1.73 m 2 ) |  |  |  |  |  |  |  |
≥ 60 | 757 | Reference | - | Reference |  | Reference | - |
45-59 | 684 | 2.11 (1.86-2.41) | < 0.001 | 1.51 (1.35-1.69) | < 0.001 | 1.50 (1.34-1.67) | < 0.001 |
30-44 | 705 | 3.02 (2.66-3.44) | < 0.001 | 1.97 (1.74-2.22) | < 0.001 | 1.96 (1.74-2.21) | < 0.001 |
< 30 | 311 | 5.27 (4.47-6.21) | < 0.001 | 2.90 (2.47-3.41) | < 0.001 | 2.83 (2.41-3.33) | < 0.001 |
ACR (μg/mg) †|  |  |  |  |  |  |  |
< 30 | 1115 | Reference | - | Reference |  | Reference | - |
30-299 | 582 | 1.58 (1.39-1.80) | < 0.001 | 1.08 (0.98-1.20) | 0.130 | 1.06 (0.96-1.19) | 0.214 |
300-999 | 338 | 1.94 (1.66-2.28) | < 0.001 | 1.09 (0.96-1.25) | 0.191 | 1.08 (0.95-1.23) | 0.238 |
≥ 1000 | 325 | 3.61 (3.08-4.23) | < 0.001 | 1.56 (1.35-1.81) | < 0.001 | 1.53 (1.32-1.77) | < 0.001 |
Phosphate (mg/dL) | Â | Â | Â | Â | Â | Â | Â |
< 3 | 265 | Reference | - | Reference |  | Reference | - |
3-3.9 | 1427 | 1.08 (0.90-1.28) | 0.419 | 1.02 (0.90-1.17) | 0.739 | 1.02 (0.90-1.17) | 0.711 |
4-4.9 | 646 | 1.59 (1.31-1.93) | < 0.001 | 1.06 (0.91-1.23) | 0.445 | 1.06 (0.92-1.24) | 0.412 |
≥ 5 | 81 | 3.51 (2.52-4.90) | < 0.001 | 1.35 (1.04-1.76) | 0.023 | 1.39 (1.08-1.81) | 0.012 |
FGF-23 ‡ |  |  |  |  |  |  |  |
Quartile I | 606 | Reference | Â | Reference | Â | Reference | Â |
Quartile II | 606 | 1.45 (1.25-1.68) | < 0.001 | 1.07 (0.96-1.20) | 0.230 | 1.08 (0.96-1.21) | 0.206 |
Quartile III | 606 | 2.11 (1.82-2.45) | < 0.001 | 1.20 (1.06-1.35) | 0.004 | 1.17 (1.04-1.33) | 0.011 |
Quartile IV | 606 | 2.62 (2.26-3.04) | < 0.001 | 1.22 (1.06-1.40) | 0.004 | 1.17 (1.02-1.34) | 0.021 |