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Table 3 Associations between non-renal factors and high sensitivity troponin t

From: Predictors of high sensitivity cardiac troponin T in chronic kidney disease patients: a cross-sectional study in the chronic renal insufficiency cohort (CRIC)

   Unadjusted Model 1 Model 2
       N* Tobit ratio (95% CI)      P Tobit ratio (95% CI)      P Tobit ratio (95% CI)      P
Age (per SD) 2,457 1.39 (1.32-1.46) < 0.001 1.31 (1.25-1.37) < 0.001 1.31 (1.25-1.37) < 0.001
Female 1,190 0.41 (0.37-0.46) < 0.001 0.38 (0.35-0.41) < 0.001 0.39 (0.36-0.42) < 0.001
Race        
Non-Hisp white 1,075 Reference - Reference - Reference -
Non-Hisp Black 946 1.51 (1.34-1.70) < 0.001 1.31 (1.20-1.43) < 0.001 1.26 (1.16-1.38) < 0.001
Hispanic 330 2.09 (1.77-2.47) < 0.001 1.06 (0.93-1.21) 0.398 1.02 (0.89-1.16) 0.768
Other 106 1.10 (0.84-1.44) 0.492 1.03 (0.84-1.25) 0.807 1.02 (0.84-1.24) 0.854
Diabetes 1,009 2.96 (2.68-3.28) < 0.001 1.87 (1.71-2.04) < 0.001 1.84 (1.69-2.00) < 0.001
Albumin (per SD) 2,437 0.72 (0.68-0.76) < 0.001 0.92 (0.88-0.96) 0.001 0.93 (0.89-0.98) 0.003
SBP (mmHg)*        
< 120 408 Reference - Reference - Reference -
120-129 324 1.32 (1.09-1.61) 0.005 1.03 (0.89-1.19) 0.678 1.03 (0.89-1.19) 0.706
130-139 321 1.69 (1.39-2.05) < 0.001 1.14 (0.98-1.32) 0.081 1.12 (0.97-1.29) 0.139
140-149 194 2.03 (1.62-2.55) < 0.001 1.24 (1.05-1.47) 0.014 1.22 (1.03-1.44) 0.023
150-159 131 2.71 (2.09-3.51) < 0.001 1.44 (1.19-1.76) < 0.001 1.38 (1.14-1.69) 0.001
≥ 160 163 3.36 (2.64-4.27) < 0.001 1.35 (1.12-1.63) 0.001 1.27 (1.06-1.53) 0.011
LV mass (g/m 2.7 ) †        
< 40 474 Reference -    Reference -
40-59 1,165 1.94 (1.68-2.24) < 0.001    1.17 (1.05-1.30) 0.006
60-79 284 3.89 (3.20-4.72) < 0.001    1.39 (1.19-1.63) < 0.001
80-99 41 3.77 (2.49-5.72) < 0.001    1.47 (1.04-1.97) 0.018
≥ 100 10 4.85 (2.15-10.95) < 0.001    1.87 (1.02-3.42) 0.043
Ejection fraction (%)        
> 50 1,845 Reference -    Reference -
46-50 197 1.12 (0.92-1.38) 0.253    1.13 (0.98-1.31) 0.087
36-45 130 1.33 (1.04-1.69) 0.023    1.13 (0.95-1.34) 0.184
≤ 35 22 1.93 (1.09-3.41) 0.024    1.64 (1.09-2.48) 0.018
  1. *N’s are # observations among participants with TnT measurements, with 7 observation excluded.
  2. Model 1 adjusted for: age (per SD), female, race, diabetes, SBP categories, albumin (per SD), eGFR_CysC, ACR, and phosphate and FGF-23. Model 2 adjusted for: Model 1 + LV Mass, ejection fraction. * Systolic blood pressure. † Left ventricular.