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Table 3 Associations between non-renal factors and high sensitivity troponin t

From: Predictors of high sensitivity cardiac troponin T in chronic kidney disease patients: a cross-sectional study in the chronic renal insufficiency cohort (CRIC)

  

Unadjusted

Model 1

Model 2

 

     N*

Tobit ratio (95% CI)

     P

Tobit ratio (95% CI)

     P

Tobit ratio (95% CI)

     P

Age (per SD)

2,457

1.39 (1.32-1.46)

< 0.001

1.31 (1.25-1.37)

< 0.001

1.31 (1.25-1.37)

< 0.001

Female

1,190

0.41 (0.37-0.46)

< 0.001

0.38 (0.35-0.41)

< 0.001

0.39 (0.36-0.42)

< 0.001

Race

       

Non-Hisp white

1,075

Reference

-

Reference

-

Reference

-

Non-Hisp Black

946

1.51 (1.34-1.70)

< 0.001

1.31 (1.20-1.43)

< 0.001

1.26 (1.16-1.38)

< 0.001

Hispanic

330

2.09 (1.77-2.47)

< 0.001

1.06 (0.93-1.21)

0.398

1.02 (0.89-1.16)

0.768

Other

106

1.10 (0.84-1.44)

0.492

1.03 (0.84-1.25)

0.807

1.02 (0.84-1.24)

0.854

Diabetes

1,009

2.96 (2.68-3.28)

< 0.001

1.87 (1.71-2.04)

< 0.001

1.84 (1.69-2.00)

< 0.001

Albumin (per SD)

2,437

0.72 (0.68-0.76)

< 0.001

0.92 (0.88-0.96)

0.001

0.93 (0.89-0.98)

0.003

SBP (mmHg)*

       

< 120

408

Reference

-

Reference

-

Reference

-

120-129

324

1.32 (1.09-1.61)

0.005

1.03 (0.89-1.19)

0.678

1.03 (0.89-1.19)

0.706

130-139

321

1.69 (1.39-2.05)

< 0.001

1.14 (0.98-1.32)

0.081

1.12 (0.97-1.29)

0.139

140-149

194

2.03 (1.62-2.55)

< 0.001

1.24 (1.05-1.47)

0.014

1.22 (1.03-1.44)

0.023

150-159

131

2.71 (2.09-3.51)

< 0.001

1.44 (1.19-1.76)

< 0.001

1.38 (1.14-1.69)

0.001

≥ 160

163

3.36 (2.64-4.27)

< 0.001

1.35 (1.12-1.63)

0.001

1.27 (1.06-1.53)

0.011

LV mass (g/m 2.7 ) †

       

< 40

474

Reference

-

  

Reference

-

40-59

1,165

1.94 (1.68-2.24)

< 0.001

  

1.17 (1.05-1.30)

0.006

60-79

284

3.89 (3.20-4.72)

< 0.001

  

1.39 (1.19-1.63)

< 0.001

80-99

41

3.77 (2.49-5.72)

< 0.001

  

1.47 (1.04-1.97)

0.018

≥ 100

10

4.85 (2.15-10.95)

< 0.001

  

1.87 (1.02-3.42)

0.043

Ejection fraction (%)

       

> 50

1,845

Reference

-

  

Reference

-

46-50

197

1.12 (0.92-1.38)

0.253

  

1.13 (0.98-1.31)

0.087

36-45

130

1.33 (1.04-1.69)

0.023

  

1.13 (0.95-1.34)

0.184

≤ 35

22

1.93 (1.09-3.41)

0.024

  

1.64 (1.09-2.48)

0.018

  1. *N’s are # observations among participants with TnT measurements, with 7 observation excluded.
  2. Model 1 adjusted for: age (per SD), female, race, diabetes, SBP categories, albumin (per SD), eGFR_CysC, ACR, and phosphate and FGF-23. Model 2 adjusted for: Model 1 + LV Mass, ejection fraction. * Systolic blood pressure. † Left ventricular.