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Table 1 First tier IRI gene candidates

From: Meta-analysis of molecular response of kidney to ischemia reperfusion injury for the identification of new candidate genes

Gene Symbol χ 2P value Wscore PubMatrix search terms
Kidney injury Kidney ischemia reperfusion injury Kidney transplantation
Lipocalin 2 LCN2 2.36E-11 33.3 314 38 57
TYRO tyrosine kinase binding protein TYROBP 5.54E-08 22.3 2 1 1
Annexin A1 ANXA1 4.52E-14 27 3 3 1
Chemokine (C-C motif) ligand 2 CCL2 3.97E-11 36 313 56 96
Heme oxygenase (decycling) 1 HMOX1 3.97E-11 27 291 100 110
Clusterin CLU 3.97E-11 25.5 27 1 11
Early growth response 2 EGR2 1.43E-10 19 0 0 0
Cyclin-dependent kinase inhibitor 1A CDKN1A 2.34E-10 26 83 16 28
Activating transcription factor 3 ATF3 1.38E-09 29 5 5 1
Chemokine (C-X-C motif) ligand 1 CXCL1 1.38E-09 25 32 18 11
ADAM metallopeptidase with TS1 ADAMTS1 1.75E-09 29 2 1 1
RAS, dexamethasone-induced 1 RASD1 5.33E-09 18 1 1 1
TIMP metallopeptidase inhibitor 1 TIMP1 8.11E-09 31 162 57 163
TNF receptor superfamily, member 12A TNFRSF12A 9.88E-09 32.5 9 1 2
Jun proto-oncogene JUN 5.52E-08 23 134 37 36
Filamin A, alpha FLNA 5.52E-08 19 0 0 0
Intercellular adhesion molecule 1 ICAM1 5.52E-08 18 352 131 244
Secreted phosphoprotein 1 SPP1 5.54E-08 24 95 7 22
Lectin, galactoside-binding, soluble, 3 LGALS3 5.54E-08 21 11 4 3
Baculoviral IAP repeat-containing 3 BIRC3 1.66E-06 14 1 0 1
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