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Table 1 Clinical characteristics of the patients at CRRT start

From: Continuous venovenous hemodiafiltration with a low citrate dose regional anticoagulation protocol and a phosphate-containing solution: effects on acid–base status and phosphate supplementation needs

Variable Protocol A (n = 20) Protocol B (n = 20) P value
Female gender 7/20 (35%) 4/20 (20%) 0.480
Age, years 72 (69–77) 70 (59–73) 0.073
Body weight, kg 72 (67–79) 70 (66–80) 0.715
Oliguric AKI § 90% 75% 0.407
Mean arterial pressure, mmHg 70 (70–80) 70 (62–80) 0.399
Use of vasopressors or inotropes 75% 85% 0.695
Mechanical ventilation 85% 90% 0.633
Artificial nutrition 95% 100% 0.311
APACHE II score 32 (29–35) 32 (27–35) 0.307
SOFA score 15 (12–16) 13 (9–14) 0.056
SOFA cardio-vascular score 3 (2–3) 3 (2–3) 0.130
Serum creatinine, mg/dl 2.10 (1.75–3.00) 2.25 (1.75–2.85) 0.469
Blood urea nitrogen, mg/dl 40.5 (26.9–62.0) 40.5 (29.0–55.2) 0.978
Hemoglobin, g/dl 10.9 (9.9–11.2) 10.0 (8.8–10.9) 0.084
Hematocrit,% 32.1 (31.2–33.4) 31.6 (27.5–34.5) 0.419
White blood cells, ×103/μl 11.0 (8.2–15.9) 12.4 (11.0–16.5) 0.664
Platelet count, ×103/μl 93 (76–177) 161 (98–254) 0.043
Antithrombin III activity,% 70 (63–78) 61 (49–78) 0.250
APTT Ratio 1.4 (1.3–1.9) 1.6 (1.4–2) 0.358
Sodium, mmol/l 139 (134–140) 139 (137–143) 0.110
Potassium, mmol/l 4.3 (4.0–4.8) 4.2 (4.1–4.8) 0.762
Total Calcium, mmol/l 2.16 (1.95–2.30) 2.03 (1.93–2.19) 0.166
Phosphorus, mmol/l 1.40 (1.07–1.58) 1.38 (1.16–1.70) 0.897
Magnesium, mmol/l 0.85 (0.75–0.93) 0.78 (0.74–0.97) 0.572
pH, units 7.38 (7.35–7.41) 7.40 (7.38–7.43) 0.324
Bicarbonate, mmol/l 21.8 (21.0–22.6) 22.2 (21.0–24.2) 0.535
Base Excess -3.5 (-4.0 to -2.0) -1.0 (-4.0 to 1.0) 0.316
pCO2, mmHg 38 (36–42) 37 (33–40) 0.992
Lactate, mmol/l 1.4 (1.0–3.0) 1.4 (1.2–2.4) 0.879
Bilirubin, mg/dl 0.89 (0.62–1.45) 0.73 (0.46–1.37) 0.376
Aspartate aminotransferase, IU/l 89 (29–608) 97 (49–376) 0.800
Alanine aminotransferase, IU/l 37 (12–325) 26 (18–75) 0.970
Albumin, g/dl 2.6 (2.4–2.8) 2.45 (2.2–2.9) 0.820
Heart surgery:    Overall
 Coronary artery bypass grafting 25% 35% 30%
 Coronary artery bypass grafting + valvular surgery 40% 15% 27.5%
 Valvular surgery 25% 20% 22.5%
 Ascending aorta replacement 10% 30% 20%
  1. Data are expressed as median (IQR) or percentage. § According to AKIN criteria (Crit Care 2007; 11:R31).