Table 2 Initial RCA-CRRT settings
RCA-CRRT settings | Protocol A | Protocol B | P-value |
|---|---|---|---|
Prescribed dialysis dose§, ml/kg/h | 28.25 (26.69–29.66) | 26.67 (25.69–28.88) | 0.333 |
Blood flow rate, ml/min | 130 (130–140) | 140 (140–140) | 0.083 |
Pre-dilution citrate solution flow rate, l/h | 1.56 (1.50–1.68) | 1.00 (1.00–1.00) | <0.001 |
Pre-dilution,% | 16.67 (16.58–16.67) | 10.64 (10.64–10.64) | <0.001 |
Post-dilution replacement fluid flow rate, l/h | 0.80 (0.80–0.95) | 0.60 (0.55–0.80) | <0.001 |
Dialysate flow rate, l/h | N/A | 0.50 (0.50–0.50) | - |
Filtration Fraction,% | 38.4 (34.5–40.3) | 27.0 (25.7–28.8) | <0.001 |
10% Calcium chloride infusion rate, mmol/h | 2.00 (1.60–2.10) | 1.90 (1.36–2.28) | 0.344 |
Citrate infusion rate, mmol/h | 18.70 (18.00–20.15) | 18.00 (18.00–18.00) | 0.051 |
Estimated citrate load, mmol/h | 12.34 (11.74–13.92) | 12.35 (12.05–12.65) | 0.471 |
Estimated citrate dose, mmol/l | 2.84 (2.74–2.91) | 2.83 (2.76–2.95) | 0.618 |