Table 4 Laboratory variables and supplementation needs during RCA-CRRT
Variable | Protocol A (n = 20) | Protocol B (n = 20) | P value |
|---|---|---|---|
Systemic Ca2+, mmol/l | 1.16 (1.10–1.23) | 1.16 (1.11–1.21) | 0.995 |
Total Calcium, mmol/l | 2.33 (2.20–2.50) | 2.33 (2.21–2.45) | 0.474 |
Calcium Ratio | 1.95 (1.84–2.09) | 1.98 (1.89–2.09) | 0.296 |
Circuit Ca2+, mmol/l | 0.37 (0.32–0.40) | 0.42 (0.36–0.47) | <0.001 |
Sodium, mmol/l | 134 (133–136) | 134 (132–135) | 0.213 |
Potassium, mmol/l | 4.2 (4.0–4.3) | 4.2 (4.0–4.4) | 0.159 |
Phosphate, mmol/l | 0.70 (0.50–1.00) | 1.20 (0.97–1.45) | <0.001 |
Magnesium, mmol/l | 0.78 (0.58–0.95) | 0.79 (0.73–0.84) | <0.001 |
pH, units | 7.40 (7.36–7.44) | 7.43 (7.40–7.46) | <0.001 |
Bicarbonate, mmol/l | 22.1 (20.9–23.5) | 25.3 (23.8–26.6) | <0.001 |
Base Excess | -3.1 (-4.6 to -1.1) | 0.9 (-0.8 to 2.4) | <0.001 |
pCO2, mmHg | 35 (32–41) | 38 (35–40) | 0.527 |
Apparent strong ion difference (AppSID), mEq/l | 37.6 (36.1–39.4) | 39.1 (37.9–40.2) | <0.001 |
Effective strong ion difference (EffSID), mEq/l | 32.0 (30.6–33.1) | 34.3 (32.8–35.9) | <0.001 |
Strong ion gap (SIG), mEq/l | 5.8 (3.5–7.7) | 4.5 (3.1–6.9) | 0.585 |
Lactate, mmol/l | 1.2 (0.9–1.6) | 1.1 (0.8–1.4) | <0.001 |
Platelet count, ×103/μl | 90 (53–156) | 187 (121–261) | <0.001 |
Antithrombin III activity,% | 72 (62–81) | 75 (63–89) | 0.078 |
aPTT Ratio | 1.4 (1.3–1.6) | 1.4 (1.2–1.7) | 0.575 |
Supplementation needs | |||
CaCl2 infusion, mmol/h | 2.18 (1.90–2.45) | 2.24 (1.97–2.58) | 0.800 |
KCl infusion, mmol/h | 5 (3–7) | 2 (0–4) | <0.001 |
Magnesium Sulphate, g/day | 3 (2–3) | 3 (3–3) | <0.001 |
Need for bicarbonate infusion, n (%) | 18/20 (90%) | 0/20 (0%) | <0.001 |
Infusion rate, mmol/h | 6 ± 6.4 | No supplementation | |
Need for phosphate supplementation, n (%) | 20/20 (100%) | 6/20 (30%) | <0.001 |
g of phosphorus/day | 3.39 ± 2.45 | 0.52 ± 1.53 |