Figure 1

The association of log-transformed troponin I and C-reactive protein with either all-cause or cardiac-specific mortality. Estimated adjusted hazard ratio (solid line) with 95% confidence intervals (dashed lines) for the association of: A) natural log-transformed troponin I (LnTnI) with all-cause mortality; B) natural log-transformed C-reactive protein (LnCRP) with all-cause mortality; C) LnTnI with cardiac-specific mortality; D) LnCRP with cardiac-specific mortality. The median level of TnI or CRP was used as a reference point for the calculation of all hazard ratios. Non-linear relationships were first examined using restricted cubic splines (knots = 3, p < 0.001 for the test of linear relation). The models are adjusted for age, time on dialysis, coronary artery disease history, diabetes mellitus status, and either LnTnI or LnCRP, as appropriate.