The ambulatory arterial stiffness index and target-organ damage in Chinese patients with chronic kidney disease

BMC Nephrology

Table 4 Multiple linear regression analysis: relationship between cardiovascular damage parameter (Left ventricular mass index, E/A ratio, Carotid intima-media thickness and Carotid aterial plaque) and AASI in CKD patients

Variables	Not standardized β	Confidence interval 95%	P value
Dependent variable: Left ventricular mass index (Adjusted R² = 0.329)
eGFR-MDRD (ml/min/1.73m²)	−0.143	−0.183 ~ -0.103	<0.001
BMI	1.392	1.020 ~ 1.764	<0.001
24h-MBP	0.163	0.012 ~ 0.313	0.034
decline ratio of bedtime SBP	−0.274	−0.451 ~ -0.096	0.003
AASI (IU)	1.712	0.191 ~ 3.233	0.027
Dependent variable: E/A ratio (Adjusted R² = 0.283)
Age	−0.014	−0.016 ~ -0.011	<0.001
24h-MBP	−0.006	−0.009 ~ -0.003	<0.001
Dependent variable: Carotid intima-media thickness (Adjusted R² = 0.305)
Age	0.009	0.008 ~ 0.010	<0.001
Sex	−0.070	−0.115 ~ -0.024	0.003

Adjusted Variables: Age; Sex: (male = 1; female = 2).
Independent variable: eGFR-MDRD (ml/min/1.73m²), BMI, 24h-MBP, decline ratio of bedtime SBP, decline ratio of bedtime DBP, AASI (IU).
(AASI: ambulatory arterial stiffness index, eGFR: estimated glomerular filtration rate, MBP: mean blood pressure; SBP: systolic blood pressure).

ISSN: 1471-2369