Table 1 Socio-demographic and clinical characteristics of study population, based upon score on the Immunosuppressive Therapy Adherence Scale (ITAS)
Characteristic | Overall | ITAS score ≤ 9 | ITAS score = 10-11 | ITAS score = 12 | P |
|---|---|---|---|---|---|
(N = 252) | (N = 36) | (N = 67) | (N = 149) | ||
Median age in years (IQR) | 54.7 (44.6-62.9) | 48.1 (38.1-61.1) | 54.6 (37.7-64.3) | 55.0 (46.3-62.6) | 0.17 |
Median years since transplant (IQR) | 2.9 (1.4-5.8) | 3.3 (2.2-5.1) | 2.7 (1.4-5.7) | 2.6 (1.3-5.9) | 0.47 |
Male, n (%) | 151 (59.9%) | 22 (61.1%) | 36 (53.7%) | 93 (62.4%) | 0.48 |
Female, n (%) | 101 (40.1%) | 14 (38.9%) | 31 (46.3%) | 56 (37.6%) | |
Race/ethnicity, n (%) | 0.79 | ||||
White | 145 (57.5%) | 20 (55.6%) | 39 (58.2%) | 86 (57.7%) | |
Black | 68 (27.0%) | 12 (33.3%) | 16 (23.9%) | 40 (26.9%) | |
Asian | 14 (5.6%) | 1 (2.8%) | 6 (9.0%) | 7 (4.7%) | |
Hispanic | 25 (9.9%) | 3 (8.3%) | 6 (9.0%) | 16 (10.7%) | |
Etiology of kidney disease, n (%) | 0.57 | ||||
Diabetes mellitus | 42 (16.7%) | 8 (22.2%) | 11 (16.4%) | 23 (15.4%) | |
Hypertension | 65 (25.8%) | 13 (36.1%) | 16 (23.9%) | 36 (24.2%) | |
Glomerulonephritis | 102 (40.5%) | 10 (27.8%) | 27 (40.3%) | 65 (43.6%) | |
Other | 43 (17.1%) | 5 (13.9%) | 13 (19.4%) | 25 (16.8%) | |
Highest education level, n (%) | 0.65 | ||||
11th grade or below | 16 (6.4%) | 3 (8.3%) | 4 (6.0%) | 9 (6.0%) | |
High school graduate or GED | 50 (19.8%) | 8 (22.2%) | 9 (13.4%) | 33 (22.2%) | |
Some college | 95 (37.7%) | 14 (38.9%) | 25 (37.3%) | 56 (37.6%) | |
College graduate or above | 90 (35.7%) | 11 (30.6%) | 28 (41.8%) | 51 (34.2%) | |
Unknown | 1 (0.4%) | 0 | 1 (1.5%) | 0 | |
Marital status, n (%) | 0.72 | ||||
Married | 167 (66.3%) | 22 (61.1%) | 42 (62.7%) | 103 (69.1%) | |
Widowed, divorced, separated, or never married | 78 (31.0%) | 13 (36.1%) | 22 (32.8%) | 43 (28.9%) | |
No response | 7 (2.8%) | 1 (2.8%) | 3 (4.5%) | 3 (2.0%) | |
Annual household income, n (%) | 0.51 | ||||
0-$34,999 | 71 (28.2%) | 15 (41.7%) | 17 (25.4%) | 39 (26.2%) | |
$35,000-$74,999 | 57 (22.6%) | 8 (22.2%) | 17 (25.4%) | 32 (21.5%) | |
$75,000 and above | 97 (38.5%) | 9 (25.0%) | 27 (40.3%) | 61 (40.9%) | |
Unknown | 27 (10.7%) | 4 (11.1%) | 6 (9.0%) | 17 (11.4%) | |
Employment status, n (%) | 0.05 | ||||
Working full-time | 92 (36.5%) | 8 (22.2%) | 27 (40.3%) | 57 (38.3%) | |
Working part-time | 36 (14.3%) | 4 (11.1%) | 12 (17.9%) | 20 (13.4%) | |
Not working | 124 (49.2%) | 24 (66.7%) | 28 (41.8%) | 72 (48.3%) | |
Primary health insurance, n (%) | 0.62 | ||||
Private insurance | 110 (43.7%) | 12 (33.3%) | 34 (50.8%) | 64 (43.0%) | |
Medicare | 106 (42.1%) | 16 (44.4%) | 24 (35.8%) | 66 (44.3%) | |
Medicaid | 27 (10.7%) | 7 (19.4%) | 6 (9.0%) | 14 (9.4%) | |
Medicaid and medicare | 7 (2.8%) | 1 (2.8%) | 2 (3.0%) | 4 (2.7%) | |
Charity or self-pay | 2 (0.8%) | 0 | 1 (1.5%) | 1 (0.7%) | |
Type of kidney transplant, n (%) | |||||
Deceased donor transplant | 94 (37.3%) | 11 (30.6%) | 22 (32.8%) | 61 (40.9%) | 0.35 |
Live donor transplant | 158 (62.7%) | 25 (69.4%) | 45 (67.2%) | 88 (59.1%) | |
On dialysis prior to transplant, n (%) | 190 (75.4%) | 28 (77.8%) | 51 (76.1%) | 111 (74.5%) | 0.84 |
Required dialysis during first post-transplant week, n (%) | 30 (11.9%) | 5 (13.9%) | 4 (6.0%) | 21 (14.1%) | 0.22 |
Acute rejection episodes since transplant, n (%) | 25 (9.9%) | 8 (22.2%) | 7 (10.5%) | 10 (6.7%) | 0.02 |
Calcineurin immunosuppressant, n (%) | |||||
Cyclosporine | 34 (13.5%) | 6 (16.7%) | 9 (13.4%) | 19 (12.8%) | 0.83 |
Tacrolimus | 217 (86.1%) | 30 (83.3%) | 58 (86.6%) | 129 *86.6%) | 0.87 |
Median serum creatinine, in mg/dL (IQR) | 1.4 (1.1-1.8) | 1.59 (1.3-2.1) | 1.35 (1.03-1.69) | 1.38 (1.11-1.79) | 0.06 |