Determinants of the creatinine clearance to glomerular filtration rate ratio in patients with chronic kidney disease: a cross-sectional study

Table 3 The association of 24-hrs urinary albumin in categorical classifications and CrCl/iGFR ratio in the regression model (N = 1342)

	Normal (24-hrs urine albumin < 30 mg; N = 515)	Microalbuminuria (24-hrs urine albumin 30 to ≦299 mg; N = 343)	Macroalbuminuria (24-hrs urine albumin 300 to ≦2999 mg; N = 378)	Nephrotic-range proteinuria (24-hrs urine albumin ≧3000 mg; N = 106)
Absolute change in CrCl/iGFR (95% CI)
Unadjusted	Reference	0.05 (−0.01—0.12)	0.02 (−0.04—0.09)	0.07 (−0.04—0.17)
Unadjusted	Reference	P = 0.12	P = 0.48	P = 0.20
Multivariate adjusted^a	Reference	0.06 (−0.01—0.13)	0.05 (−0.03—0.12)	0.11 (−0.01—0.22)
Multivariate adjusted^a	Reference	P = 0.08	P = 0.21	P = 0.07

CrCl = Creatinine clearance; IGFR = I¹²⁵ Iothalamate measured glomerular filtration rate.
^aAdjusted for age, sex, race/ethnicity, use of loop diuretics, hemoglobin A1C levels.

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