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Table 3 Diagnostic characteristics of urine NGAL for CI-AKI, stratified by baseline and postoperative time in all patient (3A), CKD stage III and CKD stage IV (3B)

From: Urinary Neutrophil Gelatinase-Associated Lipocalin predicts the severity of contrast-induced acute kidney injury in chronic kidney disease patients undergoing elective coronary procedures

3A
All patients (N = 130)     
  ROC (95% CI) Cut point (ng/ml) Sensitivity (%) Specificity (%)     
uNGAL         
baseline 0.78 (0.68 to 0.87) 75 77 74     
3 h 0.80 (0.69 to 0.89) 104 77 76     
6 h 0.85 (0.76 to 0.91) 117 94 78     
12 h 0.82 (0.74 to 0.90) 142 88 76     
18 h 0.84 (0.76 to 0.91) 161 82 76     
24 h 0.86 (0.79 to 0.93) 184 82 81     
Delta of uNGAL         
0-3 h 0.66 (0.49 to 0.79) 22 85 78     
0-6 h 0.83 (0.75 to 0.92) 45 88 80     
0-12 h 0.80 (0.72 to 0.89) 71 88 79     
0-18 h 0.78 (0.67 to 0.90) 77 82 73     
0-24 h 0.79 (0.67 to 0.91) 71 77 74     
3B
  CKD stage III (N = 100) CKD stage IV (N = 30)
  ROC (95% CI) Cut point (ng/ml) Sensitivity (%) Specificity (%) ROC (95% CI) Cut point (ng/ml) Sensitivity (%) Specificity (%)
uNGAL         
baseline 0.72 (0.61 to 0.83) 61 70 71 0.87 (0.73 to 1.0) 84 86 73
3 h 0.79 (0.65 to 0.93) 108 80 78 0.88 (0.75 to 1.0) 155 86 82
6 h 0.82 (0.72 to 0.92) 117 92 80 0.89 (0.80 to 1.0) 207 86 86
12 h 0.77 (0.67 to 0.88) 142 84 75 0.86 (0.72 to 0.99) 281 86 83
18 h 0.81 (0.72 to 0.89) 161 70 76 0.83 (0.68 to 0.97) 285 83 78
24 h 0.82 (0.74 to 0.92) 184 78 81 0.88 (0.75 to 1.0) 235 86 83
Delta of uNGAL         
0-3 h 0.80 (0.64 to 0.96) 24 90 78 0.75 (0.49 to 1.0) 22 86 78
0-6 h 0.82 (0.69 to 0.95) 42 91 79 0.89 (0.77 to 1.0) 54 100 87
0-12 h 0.76 (0.64 to 0.88) 65 82 77 0.88 (0.75 to 1.0) 71 100 83
0-18 h 0.80 (0.71 to 0.89) 77 88 73 0.73 (0.47 to 1.0) 102 86 83
0-24 h 0.81 (0.70 to 0.91) 61 80 74 0.73 (0.47 to 0.99) 91 71 78