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Table 4 Diagnostic characteristics of urine NGAL for CI-AKI stage I, stratified by baseline and postoperative time in all patient (4A), CKD stage III and CKD stage IV (4B)

From: Urinary Neutrophil Gelatinase-Associated Lipocalin predicts the severity of contrast-induced acute kidney injury in chronic kidney disease patients undergoing elective coronary procedures

4A
All Patients (N = 130)    
  ROC (95% CI) Cut point (ng/ml) Sensitivity (%) Specificity (%)    
uNGAL        
baseline 0.77 (0.65 to 0.89) 74 77 72    
3 h 0.82 (0.71 to 0.94) 108 85 76    
6 h 0.83 (0.74 to 0.92) 117 92 76    
12 h 0.82(0.72 to 0.91) 142 85 73    
18 h 0.84 (0.76 to 0.92) 161 83 74    
24 h 0.85 (0.77 to 0.93) 181 85 79    
Delta of uNGAL        
0-3 h 0.75 (0.58 to 0.91) 22 85 78    
0-6 h 0.82 (0.72 to 0.92) 54 85 80    
0-12 h 0.79 (0.68 to 0.88) 71 85 76    
0-18 h 0.77 (0.63 to 0.91) 77 92 72    
0-24 h 0.77 (0.62 to 0.92) 71 77 73    
4B
  CKD stage III (N = 100) CKD stage IV (N = 30)
  ROC (95% CI) Cut point (ng/ml) Sensitivity (%) Specificity (%) ROC (95% CI) Cut point (ng/ml) Sensitivity (%) Specificity (%)
uNGAL         
baseline 0.70 (0.58 - 0.81) 41 78 58 0.90 (0.78 - 1.0) 140 100 88
3 h 0.77 (0.62 - 0.92) 108 78 78 0.89 (0.77 - 1.0) 162 100 79
6 h 0.80 (0.70 - 0.91) 117 89 79 0.89 (0.75 - 1.0) 239 100 80
12 h 0.76 (0.69 - 0.87) 142 78 74 0.83 (0.66 1.0) 276 100 63
18 h 0.80 (0.70 - 0.89) 130 78 72 0.85 (0.68 - 1.0) 242 100 73
24 h 0.82 (0.72 - 0.92) 160 78 79 0.90 (0.78 - 1.0) 184 100 77
Delta of uNGAL         
0-3 h 0.79 (0.62 - 0.96) 24 89 77 0.81 (0.64 - 0.97) 22 100 73
0-6 h 0.80 (0.66 - 0.94) 42 89 78 0.84 (0.70 - 0.98) 65 100 77
0-12 h 0.75 (0.63 - 0.89) 74 78 77 0.82 (0.66 - 0.97) 71 100 76
0-18 h 0.81 (0.71 - 0.90) 77 89 73 0.61 (0.19 - 1.0) 102 75 73
0-24 h 0.81 (0.70 - 0.90) 71 78 77 0.62 (0.19 - 1.0) 44 75 54