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Table 5 Diagnostic characteristics of urine NGAL for CI-AKI stage II, stratified by baseline and postoperative time in all patient (5A), CKD stage III and CKD stage IV (5B)

From: Urinary Neutrophil Gelatinase-Associated Lipocalin predicts the severity of contrast-induced acute kidney injury in chronic kidney disease patients undergoing elective coronary procedures

5A
All patients (N = 130)     
  ROC (95% CI) Cut point (ng/ml) Sensitivity (%) Specificity (%)     
uNGAL         
baseline 0.76 (0.65 to 0.88) 82 100 70     
3 h 0.86 (0.76 to 0.97) 135 100 77     
6 h 0.9 (0.84 to 0.97) 264 100 87     
12 h 0.85 (0.74 to 0.96) 204 100 79     
18 h 0.8 (0.72 to 0.88) 186 100 76     
24 h 0.78 (0.7 to 0.86) 175 100 74     
Delta of uNGAL         
0-3 h 0.87 (0.77 to 0.97) 53 100 81     
0-6 h 0.93 (0.86 to 0.99) 121 100 87     
0-12 h 0.82 (0.67 to 0.98) 65 100 71     
0-18 h 0.77 (0.63 to 0.91) 83 100 67     
0-24 h 0.76 (0.64 to 0.88) 61 100 68     
5B
  CKD stage III (N = 100) CKD stage IV (N = 30)
  ROC (95% CI) Cut point (ng/ml) Sensitivity (%) Specificity (%) ROC (95% CI) Cut point (ng/ml) Sensitivity (%) Specificity (%)
uNGAL         
baseline 0.88 (0.0 to 1.0) 143 100 88 0.60 (0.42 to 0.79) 82 100 59
3 h 0.92 (0.0 to 1.0) 220 100 92 0.74 (0.48 to 1.0) 135 100 63
6 h 0.93 (0.0 to 1.0) 264 100 93 0.80 (0.56 to 1.0) 281 100 71
12 h 0.83 (0.0 to 1.0) 208 100 83 0.77 (0.51 to 1.0) 204 100 65
18 h 0.83 (0.0 to 1.0) 226 100 83 0.67 (0.48 to 0.85) 186 100 63
24 h 0.81 (0.0 to 1.0) 204 100 81 0.70 (0.52 to 0.87) 175 100 68
Delta of uNGAL         
0-3 h 0.84 (0.0 to 1.0) 77 100 84 0.88 (0.72 to 1.0) 53 100 82
0-6 h 0.90 (0.0 to 1.0) 121 100 90 0.91 (0.77 to 1.0) 197 100 86
0-12 h 0.72 (0.0 to 1.0) 65 100 72 0.88 (0.68 to 1.0) 120 100 78
0-18 h 0.69 (0.0 to 1.0) 83 100 69 0.78 (0.61 to 0.95) 102 100 71
0-24 h 0.70 (0.0 to 1.0) 61 100 70 0.79 (0.60 to 0.98) 91 100 71