Lower serum sodium level predicts higher risk of infection-related hospitalization in maintenance hemodialysis patients: an observational cohort study

Table 2 Determinants of baseline serum sodium level

	Univariate		Multivariate^a
	Coefficient	p-value	Coefficient	p-value
Age (per 5 years)	-0.008	0.886
Female (vs male)	0.426	0.147
Body mass index (per 1 kg/m²)	0.004	0.910
Smoking history	-0.078	0.793
Inability to ambulate or transfer	-0.577	0.257
Comorbid conditions
Diabetes mellitus	-1.006	0.001	-0.507	0.107
Hypertension	-0.505	0.374
Cardiovascular disease	-0.818	0.008	-0.409	0.170
Peripheral vascular disease	-1.139	0.084
Cerebrovascular disease	-0.158	0.698
Chronic liver disease	-0.395	0.380
Cancer	1.185	0.005	1.246	0.002
Dialysis vintage (per 12 months)	0.045	0.012	0.023	0.220
IDWL (per 1% of body weight)	-0.554	<0.001	-0.479	<0.001
Vascular access
Fistula	0 (ref)
Graft or catheter	-0.408	0.338
Laboratory data
Hemoglobin (per 1 g/dL)	-0.357	0.018	-0.428	0.003
Serum albumin (per 1 g/dL)	1.122	0.019	1.349	0.003
Serum creatinine (per 1 mg/dL)	0.041	0.414
Serum β2-microglobulin (per 5 mg/dL)	-0.249	0.061

^aAdjustments in all covariates, which were significantly correlated with baseline serum sodium level, with p < 0.05 at univariate analyses including diabetes mellitus, cardiovascular disease, cancer, dialysis vintage, IDWL, hemoglobin, and serum albumin.
Abbreviations: IDWL intradialytic weight loss.

ISSN: 1471-2369