| Univariate | Multivariatea | ||
---|---|---|---|---|
 | HR (95% CI) | p-value | HR (95% CI) | p-value |
Serum sodium level | Â | Â | Â | Â |
 Categorical model |  |  |  |  |
 <138.0 mEq/L | 2.06 (1.15–3.66) | 0.014 | 1.57 (0.85–2.87) | 0.148 |
 138.0 – 140.0 mEq/L | 0.94 (0.49–1.81) | 0.853 | 0.97 (0.50–1.89) | 0.938 |
 >140.0 mEq/L | 1 (ref) |  | 1 (ref) |  |
 Continuous model (per 1 mEq/L) | 0.87 (0.81–0.95) | 0.001 | 0.91 (0.83–1.00) | 0.049 |
Age (per 5 years) | 1.40 (1.25–1.57) | <0.001 | 1.24 (1.08–1.41) | 0.002 |
Female (vs male) | 0.76 (0.46–1.28) | 0.302 |  |  |
Body mass index (per 1 kg/m2) | 0.88 (0.81–0.95) | 0.001 |  |  |
Smoking history | 1.32 (0.81–2.13) | 0.267 |  |  |
Inability to ambulate or transfer | 4.13 (2.32–7.36) | <0.001 | 1.44 (0.69–2.99) | 0.328 |
Comorbid conditions | Â | Â | Â | Â |
 Diabetes mellitus | 2.80 (1.73–4.54) | <0.001 | 1.98 (1.17–3.36) | 0.011 |
 Hypertension | 1.66 (0.52–5.30) | 0.388 |  |  |
 Cardiovascular disease | 2.36 (1.47–3.80) | <0.001 | 1.65 (0.98–2.76) | 0.059 |
 Peripheral vascular disease | 3.84 (1.90–7.75) | <0.001 | 1.89 (0.88–4.06) | 0.104 |
 Cerebrovascular disease | 2.07 (1.18–3.63) | 0.011 |  |  |
 Chronic liver disease | 1.63 (0.85–3.10) | 0.140 |  |  |
 Cancer | 2.82 (1.65–4.84) | <0.001 | 2.49 (1.39–4.46) | 0.002 |
Dialysis vintage (per 12 months) | 0.99 (0.95–1.02) | 0.357 |  |  |
IDWL (per 1% of body weight) | 1.02 (0.85–1.23) | 0.824 |  |  |
Vascular access | Â | Â | Â | Â |
 Fistula | 1 (ref) |  |  |  |
 Graft or catheter | 2.14 (1.20–3.79) | 0.010 |  |  |
Laboratory data | Â | Â | Â | Â |
 Hemoglobin (per 1 g/dL) | 0.82 (0.62–1.07) | 0.140 |  |  |
 Serum albumin (per 1 g/dL) | 0.16 (0.08–0.32) | <0.001 | 0.65 (0.24–1.74) | 0.388 |
 Serum creatinine (per 1 mg/dL) | 0.76 (0.69–0.83) | <0.001 | 0.93 (0.81–1.06) | 0.272 |
 Serum β2-microglobulin (per 5 mg/dL) | 1.26 (1.03–1.54) | 0.027 |  |  |