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Table 2 Odds ratios for cross-sectional associations between vascular disease (CHD and stroke) and hypertension with different estimated renal function formulae adjusted for age and stratified by gender

From: Differences in estimation of creatinine generation between renal function estimating equations in an Indian population: cross-sectional data from the Hyderabad arm of the Indian migration study

 

Odds Ratio – unadjusted

Odds Ratio – age adjusted

 

Total

Male

Female

Total

Male

Female

Vascular Disease (Coronary Heart Disease or Stroke)

Modified Cockcroft-Gault*

0.13

0.08

0.19

0.35

0.27

0.41

 

(0.05-0.36)

(0.02-0.28)

(0.04-0.91)

(0.10-1.23)

(0.05-1.36)

(0.06-2.88)

 

p<0.001

p<0.001

p=0.037

p=0.103

p=0.111

p=0.370

MDRD*

0.13

0.07

0.22

0.22

0.11

0.38

 

(0.05-0.37)

(0.02-0.30)

(0.05-0.98)

(0.08-0.60)

(0.02-0.48)

(0.08-1.68)

 

p<0.001

p<0.001

p=0.047

p=0.003

p=0.003

p=0.197

CKD-EPI*

0.09

0.05

0.15

0.17

0.09

0.28

 

(0.03-0.26)

(0.01-0.18)

(0.03-0.68)

(0.06-0.51)

(0.02-0.39)

(0.06-1.35)

 

p<0.001

p<0.001

p=0.013

p=0.002

p=0.001

p=0.112

Rule formula*

0.09

0.05

0.15

0.18

0.10

0.27

 

(0.02-0.33)

(0.01-0.30)

(0.02-1.23)

(0.04-0.71)

(0.01-0.72)

(0.03-2.25)

 

p<0.001

p=0.001

p=0.077

p=0.015

p=0.022

p=0.225

Hypertension

Modified Cockcroft-Gault*

0.56

0.72

0.45

1.67

2.33

1.26

 

(0.36-0.87)

(0.37-1.43)

(0.23-0.89)

(0.99-2.83)

(1.03-5.28)

(0.59-2.68)

 

p=0.010

p=0.351

p=0.021

p=0.054

p=0.043

p=0.547

MDRD*

0.50

0.85

0.34

0.86

1.35

0.56

 

(0.32-0.80)

(0.43-1.67)

(0.17-0.67)

(0.53-1.41)

(0.65-2.78)

(0.28-1.14)

 

p=0.004

p=0.639

p=0.002

p=0.548

p=0.418

p=0.108

CKD-EPI*

0.27

0.50

0.13

0.76

1.38

0.36

 

(0.15-0.48)

(0.23-1.11)

(0.05-0.36)

(0.40-1.44)

(0.56-3.41)

(0.13-0.99)

 

p<0.001

p=0.088

p<0.001

p=0.394

p=0.487

p=0.048

Rule formula*

0.60

0.71

0.52

1.15

1.25

0.88

 

(0.35-1.02)

(0.32-1.59)

(0.22-1.20)

(0.66-2.03)

(0.54-2.91)

(0.38-2.05)

 

p=0.061

p=0.406

p=0.127

p=0.622

p=0.601

p=0.770

  1. *All renal function estimates underwent log base 2 transformation.