Figure 2
From: Intracellular calcium release modulates polycystin-2 trafficking
PC2 trafficking to the PM in rat proximal tubule (rPT) cells. ( A-F ) Immunocytochemistry of PC2 in rPT cells treated with control ( A ), 100 μM ouabain ( C ), or 20 nM bradykinin ( E ). Scale bars, 20 μm. Localization profile of PC along a line (as indicated) through the center of a single rPT cell treated with control ( B ), ouabain ( D ), or bradykinin ( F ). Gray areas represent PM regions. ( G ) Quantitative analysis of a number of PM PC2 positive rPT cells following indicated treatments. Values are the mean ± SEM and ***P < 0.001 vs. control.