Table 1 Clinical characteristics of study subjects by Mt5178 C/A genotype

Age (years)

54.3 ± 7.8

53.2 ± 7.8

0.171

Body mass index (kg/m²)

23.3 ± 2.8

23.5 ± 2.6

0.461

Systolic blood pressure (mmHg)

125.8 ± 15.9

125.7 ± 14.1

0.940

Diastolic blood pressure (mmHg)

74.0 ± 10.7

73.8 ± 9.1

0.823

Serum total cholesterol (mg/dl)

203.5 ± 34.3

202.1 ± 31.8

0.672

Serum HDL cholesterol (mg/dl)

54.6 ± 13.6

56.3 ± 16.2

0.269

Serum triglyceride (mg/dl)

136.7 ± 91.1

139.5 ± 90.8

0.766

Fasting plasma glucose (mg/dl)

97.2 ± 9.4

97.6 ± 9.7

0.672

Serum uric acid (mg/dl)

5.98 ± 1.21

5.93 ± 1.21

0.673

Blood urea nitrogen (mg/dl)

15.8 ± 3.7

15.2 ± 3.4

0.143

Serum creatinine (mg/dl)

0.817 ± 0.117

0.797 ± 0.111

0.090

eGFR (ml/min/1.73 m²)

79.1 ± 13.1

81.5 ± 12.4

0.066

Renal function (eGFR ≥ 90/90 > eGFR ≥ 60/eGFR < 60) (%)

17.6/77.8/4.6

25.2/72.2/2.6

0.133

Antihypertensive medications (%)

18.8

12.9

0.122

Alcohol consumption (daily drinkers/occasional drinkers/non-drinkers) (%)

46.4/35.2/18.4

47.7/38.7/13.6

0.426

Smoking status (never- or ex-/1–20 cigarettes per day/>20 cigarettes per day) (%)

59.4/29.7/10.9

59.4/25.8/14.8

0.429

Coffee consumption (≤1 cup per day/2–3 cups per day/≥4 cups per day) (%)

61.1/29.7/9.2

55.5/32.9/11.6

0.510