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Table 4 Patients with normal baseline creatinine clearance (> 60 ml/min)

From: The relationship between preoperative creatinine clearance and outcomes for patients undergoing liver transplantation: a retrospective observational study

 

Group 1 (n=15)

Group 2 (n=85)

p–value

Gender (m/f)

2/13

24/61

0.22

Age (yrs.)

58 (30–65)

52 (16–69)

0.39

BMI (kg/m2)

26.7 (23.2–36.0)

24.8 (16.0–36.2)

0.05

Hematocrit before TPL (%)

31.5 (15.3–40.0)

35.3 (21.7–49.6)

0.01

Platelets before TPL (103/μl)

83 (42–185)

92 (27–285)

0.32

MELD (corrected)

23 (6–31)

17 (7–33)

0.014

MELD (uncorrected)

21 (6–31)

12 (6–32)

0.13

CHILD (A/B/C in %)

23.1/30.8/46.1

35.4/41.8/22.8

0.20

Diabetes mellitus (%)

33.3%

16.8%

0.12

Admission from (Home/ward/ICU in %)

66.6/13.3/20.0

88.2/4.7/7.1

0.09

ASA class (II/III/IV in %)

6.7/53.3/40.0

11.8/61.2/27.0

0.55

Operating time (min)

390 (275–705)

355 (240–570)

0.11

Estimated intraoperative Blood loss (ml)

3000 (500–15000)

1000 (300–10000)

0.05

Marginal grafts (%)

46.7

35.3

0.40

Transfusion of – RBC (Unit)

2 (0–47)

3 (0–23)

0.36

- FFP (Unit)

12 (0–77)

12 (0–50)

0.62

- Platelets (Units)

1 (0–12)

0 (0–18)

0.37

- Fibrinogen (g)

2 (0–22)

0 (0–12)

0.08

Length of stay in ICU (days)

8 (3–54)

4 (2–31)

0.0003

Readmissions (%)

33.3

16.5

0.006

Incidence of Sepsis (%)

40.0

3.5

0.0001

Incidence of Respiratory Failure (w. reintubation) (%)

26.7

5.9

0.009

Reoperations (%)

40.0

10.6

0.001

Bilirubin peak (μmol/l)

157 (65–475)

87 (13–453)

0.003

ALT peak (U/l)

1625 (346–5147)

870 (133–7249)

0.02

AST peak (U/l)

1926 (389–10740)

1047 (114–13560)

0.02

  1. Data expressed as median (range) or number of patients (percentage), TPL indicates transplantation, MELD model for end stage liver disease and ICU intensive care unit, respectively.