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Table 1 Semiquantitative scoring of hyaline vacuolization in tubules and of vascular depositions in arterioles in renal cortex of rats treated for 12 weeks with cyclosporine A with/without eplerenone

From: The mineralocorticoid receptor antagonist eplerenone reduces renal interstitial fibrosis after long-term cyclosporine treatment in rat: antagonizing cyclosporine nephrotoxicity

Variable

Units

CsA

CsA + EPL

Controls

N

 

8

9

11

Semiquantitative grading

Score 0-3

2* (1–2)

1± (0–2)

0.5± (0–1)

  1. CsA: cyclosporine A. EPL: eplerenone.
  2. Results are shown as median values and range.
  3. *: p<0.05 when compared to the control group.
  4. PASx100.