Variables | Units | CsA | CsA + EPL | Controls |
---|---|---|---|---|
N | 8 | 9 | 11 | |
Increase in BW | grams/week | 13.4*± 5.2 | 22.2± 4.0 | 23.0± 5.0 |
Body weight | g | 372* ± 14 | 461 ± 16 | 486 ± 13 |
Kidney weight (right) | g | 1.4 ± 0.2 | 1.7 ± 0.2 | 1.6 ± 0.2 |
Kidney weight (total)/BW ratio | mg/g | 7.8 ± 1.6 | 7.4 ± 1.2 | 6.6 ± 0.8 |
P potassium | mmol/l | 5.1 ± 0.9 | 5.1 ± 0.4 | 4.8 ± 0.3 |
P sodium | mmol/l | 140.9 ± 4.9 | 141.7 ± 4.6 | 143.0 ± 3.7 |
P renin | mIU/l | 7.4 ± 1.9 | 12.7 ± 3.9* | 4.0 ± 1.1 |
P aldosterone | pg/ml | 65 ± 14 | 493 ± 135* | 57 ± 17 |
B cyclosporine | ng/ml | 3423 ± 549 | 2346 ± 254 | 0 |