Comparison of methodologies to define hemodialysis patients hyporesponsive to epoetin and impact on counts and characteristics

Table 1 Distributions of hyporesponsiveness definitions ^*

		Percentile
Hyporesponsiveness definition	Minimum	10th	20th	50th	80th	90th	Maximum
Monthly EPO dose	500.0	13,800.0	22,100.0	52,000.0	116,000.0	176,400.0	728,000.0
Monthly EPO dose/patient weight in kg	3.4	180.1	291.4	677.1	1534.8	2346.7	476,666.7
Resistance index^†	34.0	1140.7	1869.2	4442.3	10,361.9	16,252.3	111,815.5

EPO, erythropoietin.
^*Monthly erythropoietin dose, monthly erythropoietin dose divided by patient weight in kilograms, and monthly erythropoietin dose divided by patient hemoglobin level.
^†Monthly EPO dose divided by patient hemoglobin level.

ISSN: 1471-2369