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Table 3 Clinical characteristics of diabetic patients with any degree of CKD compared with diabetics with no CKD

From: Prevalence of chronic kidney disease in patients with type 2 diabetes in Spain: PERCEDIME2 study

 

no CKD

CKD 1‘a’

CKD 2

CKD 3A

CKD 3B

CKD 4-5

P‘b’

FG ≥ 60

FG ≥ 90

FG 89-60

FG 59-45

FG 44-30

FG < 30

ACR < 30

ACR ≥ 30

CAC ≥ 30

N = 1145 (%)

826 (72.1)

40 (3.5)

73 (6.4)

133 (11.6)

60 (5.2)

13 (1.2)

 

Age (years)

64.9 ± 10.8

62.8 ± 10.7

67.6 ± 11.1

74.4 ± 8.6

75.2 ± 10.0

73.6 ± 10.6

0.001

Gender (Men) (n%)

511 (61.9)

25 (62.5)

47 (64.4)

63 (47.4)

36 (60.0)

7 (53.8)

0.053

BMI (kg/m2)

30.1 ± 5.2

30.4 ± 4.4

30.4 ± 5.3

30.7 ± 5.1

30.9 ± 6.0

30.1 ± 5.1

0.985

Abdominal waist circumference (cm)

99.8 ± 16.5

101.7 ± 11.7

99.4 ± 19.3

99.8 ± 19.8

100.4 ± 19.1

105.5 ± 14.1

0.950

Smoking (n%)

       

  Yes

118 (14.3)

12 (30.0)

13 (17.8)

8 (6.0)

5 (8.3)

2 (15.4)

0.025

  Ex-smoker

239 (28.9)

11 (27.5)

22 (30.1)

50 (37.6)

19 (31.7)

4 (30.8)

 

  Never

469 (56.8)

17 (42.5)

38 (52.1)

75 (56.4)

36 (60.0)

7 (53.8)

 

HbA1C (%)

7.2 ± 1.2

7.8 ± 1.6

7.7 ± 1.3

7.1 ± 1.2

7.0 ± 1.0

7.9 ± 1.9

0.001

Duration of DM (years)

8.5 ± 6.5

9.5 ± 6.6

9.7 ± 7.4

11.1 ± 8.5

11.0 ± 6.9

11.7 ± 8.7

0.386

Glycaemia (mmol/L)

8.05 ± 3.20

8.84± 3.23

9.00± 2.79

7.90± 2.63

7.48± 2.98

7.88 ± 3.40

0.002

Hypertension (n%)

578 (70.0)

32 (80.0)

60 (82.2)

121 (91.0)

56 (93.3)

13 (100)

0.001

Systolic Blood Pressure (mmHg)

134.0 ± 12.5

136.9 ± 15.9

136.6 ± 15.1

135.9 ± 14.2

134.2 ± 14.1

134.5 ± 16.9

0.610

Diastolic Blood Pressure (mmHg)

77.8 ± 8.7

79.3 ± 9.9

76.3 ± 9.6

74.2 ± 10.0

72.8 ± 8.8

71.7 ± 6.6

0.003

Dyslipidaemia (n%)

555 (67.2)

27 (67.5)

52 (71.2)

97 (72.9)

37 (61.7)

8 (61.5)

0.638

Total cholesterol (mmol/L)

4.75 ± 0.95

4.94 ± 1.12

4.78 ± 0.99

4.59 ± 0.89

4.65 ± 1.11

4.30 ± 0.91

0.113

LDL cholesterol (mmol/L)

2.81 ± 0.81

2.95 ± 1.00

2.76 ± 0.79

2.67 ± 0.85

2.64 ± 0.94

2.21 ± 0.56

0.082

non-HDL cholesterol (mmol/L)

3.50 ± 0.91

3.75± 1.07

3.60 ± 1.01

3.31 ± 0.91

3.45 ± 1.08

3.22 ± 0.94

0.064

HDL cholesterol (mmol/L)

1.24 ± 0.33

1.19 ± 0.33

1.18 ± 0.26

1.28 ± 0.43

1.17 ± 0.34

1.07 ± 0.25

0.244

Triglycerides (mmol/L)

1.63 ± 0.94

1.88 ± 0.94

1.89 ± 1.21

1.76 ± 1.03

1.90 ± 0.96

2.17 ± 1.07

0.477

Plasmatic creatinine (mg/dl)

0.8 ± 0.1

0.6 ± 0.1

0.9 ± 0.1

1.1 ± 0.1

1.5 ± 0.2

2.3 ± 0.5

0.001

  1. ‘a’ CKD (1, 2, 3A, 3B, 4–5) different stages of CKD ‘b’ P (Kruskall-Wallis test, Chi-squared test).
  2. eGFR = estimated glomerular filtration rate. ACR = albumin-creatinine ratio. CKD = Chronic Kidney Disease. BMI = Body Mass Index. HbA1C = glycosilated hemoglobin. eGFR = estimated glomerular filtration rate. LDL cholesterol = Low Density Lipoprotein cholesterol. HDL cholesterol = High Density Lipoprotein cholesterol.