Table 3 Associations between presence of anti-C1q autoantibodies, levels of C1q and histopathological parameters of patients with lupus nephritis
|  | Patients with anti-C1q autoantibodies | Patients without anti-C1q autoantibodies | r value(Pvalue) | Patients with levels of C1q above 40.97 μg/ml | Patients with levels of C1q under 40.97 μg/ml | r value(Pvalue) |
|---|---|---|---|---|---|---|
Median(range) | Median(range) | Median(range) | Median(range) | |||
Histopathological data | ||||||
Activity Indices score | 9(0,19) | 7(0,16) | 0.238(<0.001) | 4(0,19) | 9(0,19) | −0.327(<0.001) |
Endocapillary hypercellularity | 3(0,3) | 2(0,3) | 0.249(<0.001) | 3(0,3) | 1(0,3) | −0.337(<0.001) |
Cellular crescents | 2(0,6) | 0(0,6) | 0.167(0.013) | 2(0,6) | 0(0,6) | −0.182(0.007) |
Karyorrhexis/fibrinoid necrosis | 2(0,6) | 0(0,4) | 0.175(0.009) | 2(0,6) | 0(0,2) | −0.310(<0.001) |
Subendothelial hyaline deposits | 1(0,3) | 1(0,3) | 0.171(0.012) | 1(0,3) | 0(0,3) | −0.312(<0.001) |
Interstitial inflammation | 1(0,3) | 1(0,3) | NS | 1(0,3) | 1(0,3) | NS |
Leukocyte infiltration | 1(0,3) | 1(0,3) | 0.159(0.019) | 1(0,3) | 1(0,3) | −0.246(<0.001) |
Chronicity Indices score | 2(0,9) | 2(0,10) | NS | 2(0,10) | 2(0,9) | NS |
Glomerular sclerosis | 0(0,3) | 0(0,3) | NS | 0(0,3) | 0(0,3) | 0.146(0.031) |
Fibrous crescents | 0(0,3) | 0(0,3) | NS | 0(0,3) | 0(0,2) | NS |
Tubular atrophy | 1(0,3) | 1(0,3) | NS | 1(0,3) | 1(0,3) | NS |
Interstitial fibrosis | 1(0,3) | 1(0,3) | NS | 1(0,3) | 1(0,3) | NS |