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Table 3 Associations between presence of anti-C1q autoantibodies, levels of C1q and histopathological parameters of patients with lupus nephritis

From: Serum levels and renal deposition of C1q complement component and its antibodies reflect disease activity of lupus nephritis

  Patients with anti-C1q autoantibodies Patients without anti-C1q autoantibodies r value(Pvalue) Patients with levels of C1q above 40.97 μg/ml Patients with levels of C1q under 40.97 μg/ml r value(Pvalue)
Median(range) Median(range) Median(range) Median(range)
Histopathological data
Activity Indices score 9(0,19) 7(0,16) 0.238(<0.001) 4(0,19) 9(0,19) −0.327(<0.001)
Endocapillary hypercellularity 3(0,3) 2(0,3) 0.249(<0.001) 3(0,3) 1(0,3) −0.337(<0.001)
Cellular crescents 2(0,6) 0(0,6) 0.167(0.013) 2(0,6) 0(0,6) −0.182(0.007)
Karyorrhexis/fibrinoid necrosis 2(0,6) 0(0,4) 0.175(0.009) 2(0,6) 0(0,2) −0.310(<0.001)
Subendothelial hyaline deposits 1(0,3) 1(0,3) 0.171(0.012) 1(0,3) 0(0,3) −0.312(<0.001)
Interstitial inflammation 1(0,3) 1(0,3) NS 1(0,3) 1(0,3) NS
Leukocyte infiltration 1(0,3) 1(0,3) 0.159(0.019) 1(0,3) 1(0,3) −0.246(<0.001)
Chronicity Indices score 2(0,9) 2(0,10) NS 2(0,10) 2(0,9) NS
Glomerular sclerosis 0(0,3) 0(0,3) NS 0(0,3) 0(0,3) 0.146(0.031)
Fibrous crescents 0(0,3) 0(0,3) NS 0(0,3) 0(0,2) NS
Tubular atrophy 1(0,3) 1(0,3) NS 1(0,3) 1(0,3) NS
Interstitial fibrosis 1(0,3) 1(0,3) NS 1(0,3) 1(0,3) NS
  1. NS, no significance.