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Table 1 Baseline patient characteristics, study population n = 1015

From: Predicting erythropoietin resistance in hemodialysis patients with type 2 diabetes

Characteristic

n

All

Non epo-resistant

Epo-resistant

Age years

1015

66 (8)

65 (8)

67 (8)

Gender % men

1015

53.9

55

41

Systolic BP mmHg

1015

145 (22)

146 (23)

147 (23)

Diastolic BP mmHg

1015

76 (11)

76 (11)

75 (11)

BMI kg/m 2

1015

27.5 (4.8)

27.6 (4.8)

26.9 (5.0)

Duration of diabetes years

953

18.1 (8.8)

17.6 (8.7)

18.5 (8.7)

Time on dialysis months

1015

8.2 (6.9)

8.6 (7.0)

7.0 (6.5)

History of

    

CAD %

1015

28,50

28,50

28,50

CHF %

1015

35.4

32.2

41.9

PVD %

1015

44.6

43.8

46.6

Smoker or ex-smoker %

1015

40.4

40.8

34.4

use of ACE-inhibitors %

1015

48

48

54

heart rate bpm

988

79 (15)

78 (15)

81 (17)

Laboratory parameters

253

25

0

100

ERI-Index > 10.1 (%)*

    

LDL cholesterol mg/dl

1015

126 (30)

126 (31)

121 (27)

AP U/I

1015

 

123 (63)

 

HDL cholesterol mg/dl

1015

36 (13)

36 (13)

37 (15)

Triglycerides mg/dl

1015

264 (167)

269 (173)

260 (172)

Hemoglobin g/dl

1015

10.9 (1.3)

11.0 (1.2)

10.3 (1.5)

Albumin g/dl

1015

3.8 (0.3)

3.8 (0.3)

3.7 (0.3)

C-reactive protein mg/l

1009

5.8 (2.3-12.4)

9.9 (15.8)

14.7 (20.8)

Calcium mmol/l

1015

2.3 (0.2)

2.3 (0.2)

2.3 (0.2)

Phosphate mg/dl

1015

6.1 (1.6)

6.1 (1.6)

6.2 (1.6)

HbA1c %

1015

6.7 (1.3)

6.7 (1.2)

6.6 (1.3)

urea mg/dl

1015

143 (36)

144 (36)

137 (35)

potassium mmol/l

1015

5.2 (0.9)

5.2 (0.8)

5.4 (1.0)

ferritin μg/L

1015

487 (426)

520 (436)

442 (405)

iron saturation %

1015

22.2 (11.3)

23.3 (11.5)

17.9 (8.7)

NT-pro-BNP pg/ml

1009

3361 (1433–9271)

7885 (14153)

9609 (14105)

Troponin T ng/ml

1009

0.09 (0.13)

0.08 (0.11)

0.11 (1.17)

ADMA umol/l

1007

0.87 (0.16)

0.86 (0.15)

0.90 (0.16)

PTH pg/mL

1008

102 (119)

101 (117)

91 (127)

25(OH)Vitamin D ng/mL

1015

17.9 (9.8)

18.2 (10.1)

16.8 (8.8)

Osteocalcin ug/l

1008

107 (102)

109 (100)

101 (100)

  1. Values are presented as mean ± SD or percentages.
  2. Abbreviations: CAD = coronary artery disease; CHF = congestive heart failure, PVD = peripheral vascular disease.
  3. BMI = body-mass index, LDL = low-density lipoprotein, HDL = high-density lipoprotein.
  4. HbA1c = glycosylated hamoglobin, NT-pro-BNP = N-terminal pro b-type natriuretic peptide.
  5. * ESA Resistance Index.
  6. Cut-off values: Q1 < 4.19; Q2 (4,20-6.64); Q3 (6.65 – 10.11); Q4 > 10.11.
  7. Patients in the upper ERI quartile were defined as ESA resistant.
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BMC Nephrology

ISSN: 1471-2369

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