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Table 2 Kt/V and echocardiographic parameters at baseline and at 2 years

From: Dynamic cardiac dyssynchrony is strongly associated with 2-year dialysis adequacy in continuous ambulatory peritoneal dialysis patients

 

Patients with an improvement in Kt/V

Patients with a worsening in Kt/V

P

n

14

34

 

Baseline

     

LVM (g)

82.2

(77.6–91.3)

188.8

(107.8–201.9)

<0.001

LVMI (g/m2)

61.8

(51.0–63.4)

95.3

(76.4–107.9)

<0.001

LVIDd (mm)

40.0

(34–44)

56.0

(47–60)

<0.001

LVIDs (mm)

25.0

(23.0–26.0)

39.0

(27.5–43.0)

0.004

LA (mm)

32.0

(25.0–39.0)

40.0

(33.5–45.0)

0.012

RV (mm)

19.0

(15.0–20.0)

22.0

(20.3–25.3)

0.002

IVS (mm)

9.0

(7.0–12.0)

12.0

(10.5–16.0)

0.002

LVPW (mm)

9.0

(8.0–9.0)

11.5

(8.8–13.0)

0.014

SWS

44.22

(33.87–63.26)

61.680

(52.00–100.02)

0.027

EDV index (ml/m2)

27.30

(24.14–39.10)

50.05

(44.70–56.30)

<0.001

ESV index (ml/m2)

8.8

(4.93–14.51)

18.00

(12.38–22.50)

<0.001

LA volume (ml)

34.6

(18.22–41.5)

68.0

(35.1–70.1)

0.002

LA volume index (ml/m2)

22.76

(13.70–28.83)

34.39

(25.78–38.10)

0.002

SDI at peak DSE (%)

0.71

(0.61–0.86)

1.51

(1.11–2.24)

<0.001

SDI at baseline (%)

1.20

(0.95–1.57)

1.35

(0.78–3.13)

0.688

EF (%)

64.0

(62.9–82.0)

62.7

(57.6–74.7)

0.056

logNT-proBNP

2.96

(2.70–3.30)

3.9

(3.23–4.50)

0.002

NT-proBNP

904.0

(502.0–1996.0)

7494.0

(2025.8–31357.0)

0.002

Kt/V

2.00

(1.96–2.06)

2.08

(1.79–2.33)

0.365

WCC

51.35

(44.93–79.83)

67.63

(61.13–79.4)

0.027

At 2 years

     

LVM (g)

101.51

(89.64–105.06)

208.07

(126.14–284.31)

<0.001

LVMI (g/m2)

69.11

(67.40–70.49)

113.08

(85.29–143.59)

<0.001

LVIDd (mm)

41.0

(37.0–44.0)

48.0

(46.3–60.0)

<0.001

LVIDs (mm)

24.0

(18.0–26.0)

30.0

(27.0–47.0)

<0.001

LA (mm)

37.0

(24.0–39.0)

44.5

(40.9–50.0)

<0.001

RV (mm)

19.0

(18.0–25.0)

25.0

(23.5–26.3)

0.001

IVS (mm)

8.0

(7.0–12.0)

13.0

(11.8–16.0)

<0.001

LVPW (mm)

9.0

(6.0–9.0)

12.0

(9.0–14.0)

<0.001

EDV index (ml/m2)

34.68

(30.03–38.82)

64.92

(51.00–75.30)

<0.001

ESV index (ml/m2)

11.3

(8.13–17.61)

23.6

(10.7–35.5)

0.056

LA volume (ml)

32.1

(22.6–51.0)

68.4

(45.8–83.3)

<0.001

LA volume index (ml/m2)

22.3

(17.0–33.5)

42.1

(32.9–45.0)

0.002

EF (%)

70.9

(54.9–73.2)

68.1

(50.6–78.5)

0.840

Kt/V

2.34

(2.02–2.41)

1.81

(1.50–2.12)

<0.001

WCC

54.65

(46.17–80.14)

60.22

(48.34–65.50)

0.482

  1. Change in Kt/V was calculated at Kt/V at 2 years – baseline Kt/V; positive changes were classified as improvements and negative changes as worsening. Values are medians (interquartile range). BSA, body surface area; IVSd, interventricular septum thickness (diastolic); LVPWd, left ventricular posterior wall thickness (diastolic); LVIDd, LV internal diameter (diastolic); LVIDs, LV internal diameter (systolic); LVMI, LV mass index; LA, left atrium; RV, right ventricle; LVEDV, LV end-diastolic volume; LVESV, LV end-systolic volume; LVEF, LV ejection fraction; SDI, systolic dyssynchrony index; NT-proBNP, N-terminal pro-B-type natriuretic peptide; WCC, weekly creatinine clearance.