Table 4 Cox regression for association between mortality of all-cause and parameters of mineral metabolism
From: Fibroblast growth factor 23, mineral metabolism and mortality among elderly men (Swedish MrOs)
Factors | Model 1 | Model 2 | Model 3 |
|---|---|---|---|
All cause mortality HR (95%CI) FGF23 | age | age, eGFR, phosphate | age, BMI, eGFR, albumin, calcium, phosphate, (PTH, FGF23 or 25D as appropriate), smoking, diabetes, hypertension, prevalent cancer, prevalent CVD |
Q1 | ref | ref | ref |
Q2 | 1.03 | 0.96 | 0.86 |
(0.75 - 1.40) | (0.72 - 1.36) | (0.60 - 1.25) | |
Q3 | 0.93 | 0.85 | 0.82 |
(0.67 - 1.29) | (0.61 - 1.38) | (0.58 - 1.16) | |
Q4 | 1.27 | 0.99 | 1.13 |
(0.94 - 1.73) | (0.71 - 1.38) | (0.80 - 1.59) | |
Log10FGF23/(1-SD) | 1.09 | 1.01 | 1.02 |
0.97-1.22 | 0.89-1.14 | 0.89-1.17 | |
Log PTH/(1-SD) | 1.16 * | 1.09 | 1.04 |
(1.03 - 1.30) | (0.97 - 1.22) | (0.92 - 1.18) | |
25D/10 nmol/L | 0.90 ** | 0.90 ** | 0.91 ** |
(0.85 - 0.95) | (0.85 - 0.95) | (0.87 - 0.97) | |
CVD mortality HR (95%CI) | |||
Q1 | ref | ref | ref |
Q2 | 1.76 * | 1.66 | 1.67 |
(1.04 - 2.96) | (0.98 - 2.83) | (0.97 - 2.88) | |
Q3 | 1.15 | 1.00 | 0.80 |
(0.64 - 2.07) | (0.55 - 1.82) | (0.42 - 1.51) | |
Q4 | 1.86 * | 1.30 | 1.37 |
(1.09 - 3.17) | (0.73 - 2.32) | (0.74 - 2.51) | |
Log10FGF23/(1-SD) | 1.43 ** | 1.26* | 1.26 |
(1.18 - 1.73) | (1.01 - 1.56) | (0.99 - 1.59) | |
Log10PTH/(1-SD) | 1.26 * | 1.13 | 1.02 |
(1.04 - 1.52) | (0.94 - 1.37) | (0.84 - 1.23) | |
25D/10 nmol/L | 0.92 * | 0.91 * | 0.94 |
(0.84 - 1.00) | (0.84 - 0.99) | (0.86 - 1.02) | |