|
Study
|
Reference range
|
N*
|
RR for high values vs. referent (95% CI)
|
Follow-up (months)†
|
|---|
|
Phosphorus (mg/dL)
|
|
Block 2004 [10]
|
4.0-5.0
|
35,783
|
1.21 (1.14-1.29)
|
18
|
|
Kalantar-Zadeh 2006 [14]
|
5.0-6.0
|
36,955
|
1.20 (1.13-1.29)
|
24
|
|
Rodriguez-Benot 2005 [24]
|
3.0-5.0
|
375
|
1.96 (1.20-3.18)
|
97.6
|
|
Tangri 2010 [30]
|
3.5-5.5
|
6,538
|
0.74 (0.53-1.03)
|
24
|
|
Calcium (mg/dL)
|
|
Block 2004 [10]
|
9.0-9.5
|
23,168
|
1.14 (1.06-1.22)
|
30
|
|
Kalantar-Zadeh 2006 [14]
|
9.0-9.5
|
36,831
|
1.06 (1.00-1.12)
|
24
|
|
Tangri 2010 [30]
|
8.4-9.5
|
6,843
|
1.23 (0.95-1.58)
|
24
|
|
Parathyroid hormone (pg/mL)
|
|
Dukkipati 2010 [29]
|
300-600
|
288
|
0.96 (0.60-1.55)
|
63
|
|
Floege 2010 [16]
|
150-300
|
2,443
|
1.35 (1.14-1.61)
|
20.9
|
|
Kalantar-Zadeh 2006 [14]
|
200-300
|
29,273
|
1.12 (1.06-1.18)
|
24
|
|
Tangri 2010 [30]
|
151-300
|
4,842
|
0.92 (0.71-1.20)
|
24
|
|
Tentori 2008 [15]
|
100-300
|
18,224
|
1.09 (1.02-1.16)
|
18.7
|
- CI, confidence interval; RR, risk ratio.
- *Sample size includes patients in the reference range plus those with relatively high biochemical parameter values.
- †The median or mean (or total, if median was not given) follow-up time in each study.
