|
Study
|
Reference range
|
N*
|
RR for low values vs. referent (95% CI)
|
Follow-up (months)†
|
|---|
|
Phosphorus (mg/dL)
|
|
Block 2004 [10]
|
4.0-5.0
|
13,478
|
1.01 (0.95-1.08)
|
18
|
|
Kalantar-Zadeh 2006 [14]
|
5.0-6.0
|
34,636
|
0.99 (0.88-1.12)
|
24
|
|
Rodriguez-Benot 2005 [24]
|
3.0-5.0
|
170
|
0.41 (0.05-3.26)
|
97.6
|
|
Tangri 2011 [30]
|
3.5-5.5
|
4,776
|
1.22 (1.01-1.49)
|
24
|
|
Calcium (mg/dL)
|
|
Block 2004 [10]
|
9.0-9.5
|
28,129
|
0.81 (0.77-0.85)
|
30
|
|
Kalantar-Zadeh 2006 [14]
|
9.0-9.5
|
37,662
|
0.93 (0.87-0.98)
|
24
|
|
Tangri 2011 [30]
|
8.4-9.5
|
3,394
|
1.35 (0.24-7.48)
|
24
|
|
Parathyroid hormone (pg/mL)
|
|
Dukkipati 2010 [29]
|
300-600
|
648
|
0.72 (0.52-0.95)
|
63
|
|
Floege 2010 [16]
|
150-300
|
2,595
|
1.31 (1.14-1.51)
|
20.9
|
|
Kalantar-Zadeh 2006 [14]
|
200-300
|
33,758
|
0.99 (0.94-1.05)
|
24
|
|
Tangri 2011 [30]
|
151-300
|
5,071
|
0.84 (0.61-1.16)
|
24
|
|
Tentori 2008 [15]
|
100-300
|
17,648
|
1.00 (0.93-1.08)
|
18.7
|
- CI, confidence interval; RR, risk ratio.
- *Sample size includes patients in the reference range plus those with relatively low biochemical parameter values.
- †The median or mean (or total, if median was not given) follow-up time in each study.
