Table 4 Multivariate Cox regression analysis of renal progression with the estimated contribution of each covariates to the prediction

eGFR ≥ 45 ml/min/1.73 m2

  Diabetes (yes vs. no)

1.91 (1.18 - 2.11)

0.035

1.11

  Hypoalbuminemia (yes vs. no)

3.25 (1.73 - 4.61)

<0.001

6.91

  CVD (yes vs. no)

2.81 (2.61 - 4.82)

0.004

2.39

eGFR < 45 ml/min/1.73 m2

Model 1

  Age

0.98 (0.97 - 0.99)

<0.001

0.70

  Gender (male vs. female)

0.93 (0.74 - 1.18)

0.059

0.10

  Diabetes (yes vs. no)

1.71 (1.42 - 2.34)

<0.001

1.29

  CKD stage

2.67 (2.19 - 3.26)

<0.001

7.67

  Metabolic complications (≥3 vs. <3)

2.18 (1.48 - 3.22)

<0.001

0.51

Model 2

  Age

0.98 (0.97 - 0.99)

<0.001

0.74

  Gender (male vs. female)

1.05 (0.81 - 1.37)

0.704

<0.001

  CKD stage

2.30 (1.87 - 2.83)

<0.001

5.68

  CVD (yes vs. no)

3.29 (1.56 - 6.99)

0.002

0.29

  Hyperphosphatemia (yes vs. no)

2.09 (1.57 - 2.80)

<0.001

1.26

  Hyperparathyroidism (yes vs. no)

0.92 (0.64- 1.31)

0.633

<0.001

  Anemia (yes vs. no)

2.64 (1.38 - 5.01)

0.003

0.41

  Hyperuricemia (yes vs. no)

1.03 (0.78 - 1.35)

0.857

<0.001

  Hypoalbuminemia (yes vs. no)

2.58 (2.04 - 3.57)

<0.001

4.54

  Acidosis (yes vs. no)

1.24 (0.93 - 1.67)

0.15

<0.001

  Microinflammation (yes vs. no)

1.36 (1.02 - 1.80)

0.038

0.15