Table 5 Multivariate Cox regression analysis of all-cause mortality with estimated contribution of each covariate to the prediction

eGFR ≥ 45 ml/min/1.73 m2

  Age

1.11 (1.03 - 1.19)

0.006

16.13

  Hypoalbuminemia (yes vs. no)

5.87 (1.22- 8.21)

0.001

5.61

  Microinflammation (yes vs. no)

3.31 (1.61 - 7.82)

0.027

4.45

eGFR < 45 ml/min/1.73 m2

Model 1

  Age

1.06 (1.04 - 1.08)

<0.001

3.70

  Gender (male vs. female)

0.84 (0.59 - 1.21)

0.36

<0.001

  Diabetes (yes vs. no)

1.36 (094–1.97)

0.126

<0.001

  CKD stage

1.13 (0.91 - 1.41)

0.279

<0.001

  Metabolic complications (≥3 vs. <3)

3.71 (2.35 - 5.87)

<0.001

2.60

Model 2

  Age

1.07 (1.47 - 1.09)

<0.001

5.00

  Gender (male vs. female)

0.66 (0.45 - 0.10)

0.061

0.14

  CKD stage

1.37 (1.07 - 1.75)

0.012

0.68

  CVD (yes vs. no)

1.86 (1.09 - 3.19)

0.024

0.39

  Hyperphosphatemia (yes vs. no)

0.98 (6.23 - 1.55)

0.939

<0.001

  Hyperparathyroidism (yes vs. no)

1.36 (0.97 - 2.42)

0.223

<0.001

  Anemia (yes vs. no)

1.10 (0.61 - 2.00)

0.924

<0.001

  Hyperuricemia (yes vs. no)

2.09 (1.39 - 3.13)

<0.001

1.37

  Hypoalbuminemia (yes vs. no)

2.39 (1.54 - 3.69)

<0.001

2.11

  Acidosis (yes vs. no)

1.37 (0.87 - 2.17)

0.173

<0.001

  Microinflammation (yes vs. no)

1.46 (0.95 - 2.24)

0.083

<0.001