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Table 2 Cytotoxicity following exposure of the HK-2 cells in two different media to a panel of engineered nanomaterials

From: An in vitroassessment of panel of engineered nanomaterials using a human renal cell line: cytotoxicity, pro-inflammatory response, oxidative stress and genotoxicity

NM K-SFM RPMI-FCS
  LC20 LC50 LC20 LC50
NM 111 0.8 μg/cm2 2.5 μg/cm2 0.5 μg/cm2 0.9 μg/cm2
NM 110 0.64 μg/cm2 2.5 μg/cm2 0.64 μg/cm2 1 μg/cm2
NM 300 1.25 μg/cm2 10 μg/cm2 1.25 μg/cm2 4.5 μg/cm2
NM 400 2.5 μg/cm2 Not reached up to 80 μg/cm2 20 μg/cm2 Not reached up to 80 μg/cm2
NM 402 4.5 μg/cm2 Not reached up to 80 μg/cm2 20 μg/cm2 Not reached up to 80 μg/cm2
NRCWE 002 20 μg/cm2 Not reached up to 80 μg/cm2 Not reached up to 80 μg/cm2 Not reached up to 80 μg/cm2
NRCWE 001 40 μg/cm2 Not reached up to 80 μg/cm2 Not reached up to 80 μg/cm2 Not reached up to 80 μg/cm2
NRCWE 004 40 μg/cm2 Not reached up to 80 μg/cm2 Not reached up to 80 μg/cm2 Not reached up to 80 μg/cm2
NRCWE 003 60 μg/cm2 Not reached up to 80 μg/cm2 Not reached up to 80 μg/cm2 Not reached up to 80 μg/cm2
NM 101 Not reached up to 80 μg/cm2 Not reached up to 80 μg/cm2 Not reached up to 80 μg/cm2 80 μg/cm2
  1. The cells were exposed to the NM for 24 hr with cytotoxicity measured via WST-1 (NMs ranked in order of cytotoxicity to HK-2 cells – high to low).