Figure 2
From: Dipeptidyl peptidase IV inhibitor attenuates kidney injury in rat remnant kidney
Effects of sitagliptin on DPP IV activity and GLP-1 receptor expression. DPP IV enzymatic activity in serum of rats from each group (A). Representative western blot and group data showing GLP-1 receptor protein abundance in the kidneys of rats from each group (B). The intensity of the bands corresponding to the GLP-1 receptor was corrected by β-actin levels to obtain relative measures of GLP-1 receptor expression among all samples. The results are expressed as the mean ± s.d. *Significantly different with respect to the sham-operated rats; #significantly different with respect to the nephrectomized rats; *# P < 0.05. Sham, sham operation; Nx, nephrectomy; Nx+STG, nephrectomy and sitagliptin treatment.