Figure 6From: Dipeptidyl peptidase IV inhibitor attenuates kidney injury in rat remnant kidney Effects of sitagliptin on apoptosis. Apoptotic cells detected in the kidneys stained with TUNEL (A). Representative western blot and group data showing cleaved caspase-3, cleaved caspase-9, and Bax protein abundance in the kidneys of rats from each group (B). The intensity of the bands corresponding to cleaved caspase-3, cleaved caspase-9, and Bax was corrected by β-actin levels. The results are expressed as the mean ± s.d. *Significantly different with respect to the sham-operated rats; #significantly different with respect to the nephrectomized rats; *# P < 0.05. Sham, sham operation; Nx, nephrectomy; Nx+STG, nephrectomy and sitagliptin treatment. Magnification × 200.Back to article page