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Table 2 Summary of kidney function and outcomes stratified by severity of AKI

From: Risk factors and outcomes associated with acute kidney injury following ruptured abdominal aortic aneurysm

 

All

No AKI

AKIN stage 1

AKIN stage 2

AKIN stage 3

P¶

 

(n = 140)

(n = 34)

(n = 47)

(n = 36)

(n = 23)

 

Baseline SCr (μmol/L) (median [IQR])

92 (81–110)

89 (80–103)

98 (83–118)

87 (80–112)

100 (85–124)

0.12

Baseline eGFR < 60 mL/min/1.73 m2 (no, %)

50 (35.5)

11 (26.2)

20 (42.6)

12 (38.7)

7 (33.3)

0.424

Baseline eGFR (mL/min/1.73 m2) (mean [SD])

65 (21)

71 (19)

60 (22)

67 (21)

63 (18)

0.078

Urine output (24 hr) (mL) (mean [SD])

1642 (1165)

1970 (852)

1809 (1315)

1357 (1234)

1266 (978)

0.04

Oliguria (< 400 mL/24 hr) (n, %)

16 (11.5)

0 (0)

3 (6.5)

8 (22.2)

5 (21.7)

0.003

Peak SCr (μmol/L) (median [IQR])

169 (123–277)

102 (90–122)

155 (135–190)

219 (175–262)

460 (358–460)

0.0001

Delta SCr (baseline to peak) (μmol/L) (median [IQR])

77 (31–139)

15 (4–22)

55 (42–80)

127 (94–148)

370 (278–464)

0.0001

Time to Peak SCr (d) (median [IQR])

1 (0–5)

-

1 (0–2)

1 (0–3)

6 (2–15)

0.0001

RRT (n, %)

19 (13.6)

0 (0)

2 (4.3)

4 (11.1)

13 (56.5)

< 0.001

Discharge SCr (μmol/L) (median [IQR])

107 (83–184)

82 (73–90)

108 (86–108)

112 (83–194)

244 (148–412)

0.0001

Discharge SCr* (μmol/L) (median [IQR])

87 (79–112)

82 (73–90)

96 (85–112)

85 (73–112)

168 (116–278)

0.0001

Delta SCr (baseline to discharge)* (μmol/L) (median [IQR])

1 (−9 – 16)

6 (−9 – 13)

0 (−2 – 26)

24 (0–96)

92 (42–189)

0.0001

RRT at hospital discharge (n, %)

4 (17.4)

0 (0)

0 (0)

0 (0)

4 (17.4)

0.001

ICU Mortality (n, %)

30 (21.4)

0 (0)

11 (23.4)

12 (33.3)

7 (30.4)

< 0.001

Hospital Mortality (n, %)

38 (27.1)

0 (0)

13 (27.6)

14 (38.9)

11 (47.8)

< 0.001

ICU stay (d) (median [IQR])

4 (2–9)

3 (2–5)

3 (1–7)

4 (2–10)

14 (7–23)

< 0.001

Hospital stay (d) (median [IQR])

11 (7–19)

9 (7–11)

10 (7–16)

11 (3–24)

23 (13–32)

< 0.001

  1. Abbreviations: SCr = serum creatinine; eGFR = estimated glomerular filtration rate; RRT = renal replacement therapy.
  2. *Survivors and RRT independent.
  3. ¶ P-value for comparison across groups.
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BMC Nephrology

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