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Figure 5 | BMC Nephrology

Figure 5

From: Abnormal urinary excretion of NKCC2 and AQP2 in response to hypertonic saline in chronic kidney disease: an intervention study in patients with chronic kidney disease and healthy controls

Figure 5

Effects of 3% hypertonic saline on plasma concentrations of Renin (A), angiotensin II (B), aldosterone (C) and vasopressin (D). PRC, p-ang II and p-aldo are presented as medians ±25th and 75th percentiles. P-AVP is mean ± SEM. A-C: Both groups decreased in response to hypertonic saline. PRC and p-Aldo were significant higher in the patient group. D: There was a significant difference in p-AVP between groups, but the response to hypertonic saline did not differ (pGLM-RM = 0.970). Independent-samples t-test or Man Whitney U test in CKD patients vs. controls *p = 0.01, **p < 0.0001.

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