TY - JOUR AU - François, Karlien AU - Wissing, Karl Martin AU - Jacobs, Rita AU - Boone, Dries AU - Jacobs, Kristine AU - Tielemans, Christian PY - 2014 DA - 2014/07/03 TI - Avoidance of systemic anticoagulation during intermittent haemodialysis with heparin-grafted polyacrilonitrile membrane and citrate-enriched dialysate: a retrospective cohort study JO - BMC Nephrology SP - 104 VL - 15 IS - 1 AB - Since October 2010, the combination of a heparin-grafted polyacrilonitrile (AN69ST) membrane with a 0.80 mmol/L citric acid-containing dialysate is routinely used in our centre for intermittent haemodialysis, without systemic anticoagulation, in critically ill patients with increased bleeding risk. The primary outcome of this retrospective cohort study was to assess the development of circuit clotting during these dialysis procedures. Secondly, we assessed the impact of clotting on treatment duration, the incidence rate of coagulation-induced retransfusion failure and the association of patient and dialysis characteristics with the occurrence of clotting. SN - 1471-2369 UR - https://doi.org/10.1186/1471-2369-15-104 DO - 10.1186/1471-2369-15-104 ID - François2014 ER -