Skip to main content

Table 2 Plasma uric acid levels associated with tubular atrophy/interstitial fibrosis in IgA nephropathy

From: Plasma uric acid level indicates tubular interstitial leisions at early stage of IgA nephropathy

 

The whole cohort

 

Subgroup

(eGFR > =90 ml/min/1.73 m2)

P

 

PUA (μmol/L)

P

PUA (μmol/L)

  

Oxford score

T0 (N = 494)

359.2+/−4.8

 

T0 (N = 246)

335.9+/−6.9

 

T1 (N = 59)

411.9+/−13.8

0.012

T1 (N = 8)

363.4+/−35.8

0.256

T2 (N = 70)

449.1+/−12.8

 

T2 (N = 4)

416.7+/−53.7

 

Tadj_Ox

Tadj_Ox0

359.2+/−4.8

 

Tadj_Ox0 (N = 246)

335.9+/−6.9

 

(N = 494)

     

Tadj_Ox1

432.1+/−9.4

1.5*10 -11

Tadj_Ox1 (N = 12)

349.8+/−2.8

0.150

(N = 129)

     

Beijing score

T0 (N = 46)

340.9+/−15.5

 

T0 (N = 34)

335.9+/−18.3

 

T1 (N = 332)

351.9+/−5.8

 

T1 (N = 175)

328.5+/−8.1

 

T2 (N = 118)

387.0+/−9.7

4.8*10-4

T2 (N = 37)

371.8+/−17.6

3.4*10-5

T3 (N = 57)

413.7+/−13.9

 

T3 (N = 8)

363.8+/−37.8

 

T4 (N = 70)

449.1+/−12.6

 

T4 (N = 4)

416.7+/−53.7

 

Tadj_Bj

Tadj_Bj0

350.5+/−5.5

 

Tadj_Bj0 (N = 209)

329.7+/−7.4

 

(N = 378)

     

Tadj_Bj1

411.0+/−6.8

0.004

Tadj_Bj1 (N = 49)

374.2+/−15.2

2.3*10 -4

(N = 245)

     
  1. Data was presented as Mean ± SEM. Analyses were performed with univariate analysis in the whole cohort and the subgroup. PUA: plasma uric acid. Tubular atrophy/ interstitial fibrosis was analyzed as Oxford score, Beijing score separately, and adjusted by age, gender, BMI, eGFR, proteinuria, drug therapy and other pathological items. Tadj_Ox: all individuals were re-attributed into two groups, according to 25% interstitial fibrosis/tubular atrophy (Tadj_Ox0 <= 25%, Tadj_Ox1 > 25%), or to 10% interstitial fibrosis/tubular atrophy (Tadj_Bj0 < 10%, Tadj_Bj1 >= 10%).