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Table 3 Parameter comparison pre-LMWID and post-LMWID infusion stratified by darbepoetin administration

From: Iron repletion is associated with reduction in platelet counts in non-dialysis chronic kidney disease patients independent of erythropoiesis-stimulating agent use: a retrospective cohort study

Darbepoetin (N = 94)

Parameter

Pre-infusion

30 days

p-value

60 days

p-value

 

Mean ± SD

Mean ± SD

 

Mean ± SD

 

Platelet count (1000/mm3)

304.53 ± 106.97

274.26 ± 136.27

0.008

254.41 ± 80.16

<0.0001

Hemoglobin (g/dL)

9.98 ± 1.22

11.12 ± 1.61

<0.0001

11.22 ± 1.70

<0.0001

Ferritin (ng/mL)

43.07 ± 36.05

208.06 ± 171.79

<0.0001

150.58 ± 151.79

<0.0001

Transferrin saturation (%)

13.07 ± 6.26

24.32 ± 12.83

<0.0001

25.83 ± 13.55

<0.0001

No Darbepoetin (N = 14)

Parameter

Pre-infusion

30 days

p-value

60 days

p-value

Mean ± SD

Mean ± SD

Mean ± SD

Platelet count (1000/mm3)

313.71 ± 124.87

279.00 ± 130.08

0.0021

263.43 ± 72.68

0.0256

Hemoglobin (g/dL)

11.44 ± 1.43

12.66 ± 1.51

0.0049

12.46 ± 1.30

0.0053

Ferritin (ng/mL)

33.50 ± 23.10

135.00 ± 103.01

0.0276

192.25 ± 208.21

0.0620

Transferrin saturation (%)

12.71 ± 4.41

16.00 ± 6.07

0.1047

16.75 ± 5.92

0.0683

  1. LMWID = low molecular weight iron dextran.
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BMC Nephrology

ISSN: 1471-2369

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