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Table 4 Parameter comparison pre-LMWID and 60 days post-LMWID infusion stratified by iron dextran dose

From: Iron repletion is associated with reduction in platelet counts in non-dialysis chronic kidney disease patients independent of erythropoiesis-stimulating agent use: a retrospective cohort study

 

Iron dextran 1000 mg

Iron dextran 500 mg

N = 65

N = 43

 

Pre-infusion

Post-infusion

P value

Pre-infusion

Post-infusion

P value

Mean ± SD

Mean ± SD

Mean ± SD

Mean ± SD

Platelet count (1000/mm3)

323.54 ± 118.82

273.52 ± 87.34

<0.0001

278.79 ± 86.27

228.47 ± 54.87

<0.0001

Hemoglobin (g/dL)

10.24 ± 1.41

11.60 ± 1.63

<0.0001

10.07 ± 1.23

11.04 ± 1.78

0.0001

Ferritin (ng/mL)

46.22 ± 38.31

174.60 ± 158.25

<0.0001

35.21 ± 27.54

122.59 ± 150.15

0.0005

Transferrin saturation (%)

13.60 ± 6.43

24.95 ± 12.12

<0.0001

12.16 ± 5.34

25.24 ± 15.07

<0.0001

  1. LMWID = low molecular weight iron dextran.