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Table 7 Time from reperfusion to day 1 serum sampling

From: Serum neutrophil gelatinase-associated lipocalin and recovery of kidney graft function after transplantation

Sample time after reperfusion

Mean sNGAL ng/ml EGF (SD)

Mean sNGAL ng/ml DGF (SD)

p-valueDGF vs EGF

ROC-analysis AUC, p-value, CIoptimal cut-off value, sensitivity, specificity

<6 hours

n = 9

n = 9

0.002

1.00, p = 0.001, CI 1.00-1.00

 

278 (78.8)

687 (239.4)

 

436 ng/ml, 100%, 100%

7 to 12 hours

n = 46

n = 36

<0.0001

0.864, p < 0.0001, CI 0.783-0.946

 

365 (159.5)

594 (169.2)

 

420 ng/ml, 94%, 73%

>12 hours

n = 47

n = 23

<0.0001

0.920, p < 0.0001, CI 0.838-0.999

 

321 (125.0)

526 (187.9)

 

420 ng/ml, 91%, 83%

  1. EGF = early graft function, DGF = delayed graft function, AUC = area under the curve, CI = confidence interval. Delayed graft function defined according to the conventional definition: i.e. the need for dialysis during the first week after transplantation.
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BMC Nephrology

ISSN: 1471-2369

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