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Table 2 Laboratory and pathological findings in the DFPP and IA groups

From: Comparison of double filtration plasmapheresis with immunoadsorption therapy in patients with anti-glomerular basement membrane nephritis

 

DFPP group (n = 15)

IA group (n = 12)

p

WBC (109/L)

9.39 ± 4.64

8.25 ± 3.17

0.458

Hemoglobin (g/dl)

85.4 ± 19.6

85.1 ± 13.0

0.626

Platelets (109/L)

297 ± 174

235 ± 127

0.137

Urin protein (g/24 hr)

2.85 ± 1.74

1.59 ± 1.36

0.053

Microscopic hematuria (105/ml)

2200 (950 ~ 5000)

1725 (1300 ~ 2965)

0.207

Serum albumin (g/L)

34.6 ± 4.3

35.1 ± 5.7

0.754

Serum globulin (g/L)

26.3 ± 6.7

27.1 ± 8.1

0.693

BUN (umol/L)

3.76 ± 1.44

3.12 ± 2.09

0.104

pSCr (umol/L)

826 ± 315

795 ± 437

0.430

SCr (umol/L)

551 ± 335

490 ± 445

0.353

UA (umol/L)

417 ± 188

470 ± 135

0.329

Disorders of Ca/P

12 (75.0%)

7 (58.3%)

0.218

CRP (mg/L)

25.7 (2.1 ~ 102.6)

8.8 (0.1 ~ 53.6)

0.102

High CRP

12 (75.0%)

6 (50.0%)

0.432

CD4 (n/ml)

433 ± 182

367 ± 187

0.306

CD8 (n/ml)

386 ± 233

325 ± 397

0.071

Crescent (%)

81.5 (68.1 ~ 100)

60.8 (45.8 ~ 87.9)

0.056

Cellular crescent (%)

17.4 (1.3 ~ 32.3)

14.8 (1.1 ~ 75.8)

0.536

Fibrous/ fibrocellular crescents (%)

52.25 (39.2 ~ 76.6)

41.1 (12.7 ~ 75.8)

0.538

Vascular loop necrosis

11 (68.8%)

9 (75.0%)

0.655

Bowman’s wall fracture

14 (87.5%)

11 (91.7%)

0.691

Acute interstitial lesions

2.00 ± 0.73

1.50 ± 1.24

0.251

Chronic interstitial lesions

1.88 ± 1.02

2.00 ± 0.73

0.107

Tubular atrophy

2.50 ± 0.73

2.08 ± 1.08

0.520

Interstitial cell infiltration

2.00 ± 0.73

1.50 ± 1.24

0.133

Tubulitis

1.88 ± 1.02

2.00 ± 0.73

0.675

Interstitial Fibrosis

2.50 ± 0.73

2.08 ± 1.08

0.730

Stromal vascular lesions

10 (62.5%)

7 (58.3%)

0.754

  1. SCr, serum creatinine; BUN, bloodureanitrogen; UA, uric acid; pSCr, highest serum creatinine in the course.