Inclusion criteria | Exclusion criteria |
---|---|
• Age ≥ 18 years | • Any major cardiovascular event within the last 6 months prior to enrolment (this includes, but is not limited to, new onset arrhythmia, hospitalization for a cardiovascular complication) |
• Thrice weekly hemodialysis outpatient within the Southern Alberta Renal Program |  |
• Physician consent to participate | • Refusal to cease vitamin D therapy for four (4) weeks prior to initiation of the study |
• Ability and agreement to cease any prior vitamin D medication for four (4) weeks prior to initiation of the study | • Palliative status or metastatic malignancy |
• Ability to comprehend study protocol and provide oral and written consent in English (native language or translated) | • Known or anticipated upcoming change in dialysis modality including transfer to peritoneal dialysis, kidney transplant, or change in current hemodialysis schedule/duration |