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Table 1 Baseline characteristics

From: The influence of vitamin D analogs on calcification modulators, N-terminal pro-B-type natriuretic peptide and inflammatory markers in hemodialysis patients: a randomized crossover study

 

Alfacalcidol-paricalcitol

Paricalcitol-alfacalcidol

n = 26

n = 31

Age (years ± SD)

66.7 ± 10.8

67.1 ± 13.1

Gender (male/female)

17/9

17/12

Race: Caucasian

26(100%)

29(100%)

Time on dialysis (month; median (range))

36.5 (4-236)

36.0(3-132)

Etiology of ESRD

  

  Diabetes

1(4%)

5(17%)

  Nephrosclerosis

4(15%)

6(21%)

  Polycystic

5(19%)

3(10%)

  Chronic glomerulonephritis

5(19%)

4(14%)

  Chronic interstitial

2(8%)

2(7%)

  Postrenal

4(15%)

3(10%)

  Unknown

5(19%)

6(21%)

Cardiovascular history

  

  Hypertension

20(77%)

22(76%)

  Diabetes

2(8%)

5(17%)

  Ischemic heart disease

9(35%)

10(34%)

  Stroke or TCI

3(12%)

7(24%)

  Heart failure

4(15%)

4(14%)

Biochemical

  

  s-FGF23 (pg/ml (median (range)))

2952(95-25543)

2480(117-32650)

  p-intact PTH (pg/ml ± SD)

568(246)

523(175)

  p-calcium ion (mmol/l ± SD)

1.16(0.08)

1.15(0.08)

  p-phosphate (mmol/l ± SD)

1.50(0.23)

1.49(0.27)

  p-25hydroxyvitamin D2 + D3 (nmol/l ± SD)

43.4(24.3)

34.3(22.0)