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Figure 1 | BMC Nephrology

Figure 1

From: Benazepril affects integrin-linked kinase and smooth muscle α-actin expression in diabetic rat glomerulus and cultured mesangial cells

Figure 1

Renal histology. (A-C) H&E stained kidney sections of the normal control (NC), diabetic nephropathy group (DN), and diabetic nephropathy treated with benazepril (ACEI). DN and ACEI groups showing the typical structures of the glomeruli and tubules. (D-F) Periodic acid-Schiff (PAS) staining was performed in the kidneys of the different groups. (G) Quantification of glomerular PAS staining. (H-J) CD68 immunohistochemistry staining in the kidneys of the different groups. (K) Quantification of glomerular staining for CD68. (L-N) CD3ϵ immunohistochemistry staining in the kidneys of the different groups. (O) Quantification of glomerular staining for CD3ϵ. An increase in mesangial area was observed in DN rat mice as compared with control rat. The ACEI group that treated with Benazepril showed less inflammatory cells, less thickening of basement membrane and capillaries. n = 12. Bars = 50 μm. *, P < 0.05 vs. control; #, P < 0.05 vs. DN.

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BMC Nephrology

ISSN: 1471-2369

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