Figure 2
Benazepril affects the TGF-β 1 , ILK and α-SMA expression in renal tissue and glomeruli. (A-C) Immunohistochemistry staining of TGF-β1 in the rat kidneys of the NC, DN and ACEI groups. (D-F) Immunofluorescence staining of ILK in rat kidneys of NC, DN and ACEI group. There are significant increases in ILK expression in DN rat compared with control mice. Rabbit IgG was used as a negative control and shown in the right corner of each figure. (G-I) Immunofluorescence staining of α-SMA in the rat kidneys of the different groups. There are significant increases in α-SMA expression in DN rat compared with control mice. Mouse IgG was used as a negative control and is shown in the right corner of each figure. Bars = 50 μm.