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Table 3 Unadjusted and adjusted hazard ratio for mortality or ESRD and 95% CI among participants with CKD in the REGARDS study, n = 2,761

From: The association between race and income on risk of mortality in patients with moderate chronic kidney disease

 

HR (95% CI) model 1 unadjusted

HR (95% CI) model 2 adjusted for sociodemographicsa

HR (95% CI) model 3 + CKD stage

HR (95% CI) model 4 + BMI and smoking

HR (95% CI) model 5 + comorbidityb

HR (95% CI) model 6 + area level measuresc

HR (95% CI) model 7 + BP and albuminuriad

Income

       

Medium/High

1.00

1.00

1.00

1.00

1.00

1.00

1.00

Lowe

1.52 (1.32-1.75)

1.62 (1.40-1.88)

1.46 (1.26-1.70)

1.40 (1.20-1.63)

1.29 (1.10-1.50)

1.28 (1.09-1.51)

1.32 (1.06-1.65)

Race

       

White

1.00

1.00

1.00

1.00

1.00

1.00

1.00

Black

1.45 (1.27-1.66)

1.57 (1.37-1.80)

1.52 (1.32-1.75)

1.55 (1.35-1.79)

1.52 (1.31-1.77)

1.52 (1.30-1.78)

1.63 (1.31-2.01)

  1. aSociodemographic characteristics include age, geographic location, education and gender.
  2. bComorbidities include heart disease, hypertension, and diabetes.
  3. cArea Level measures include county poverty and Gini Index. The Gini Index, a measure of income heterogeneity which ranges from 0 to 1, was considered with 0 indicating perfectly equal income distribution across households in a county and 1 indicating all county income was held within one household.
  4. dBlood pressure (BP) included systolic and diastolic blood pressure. Serum albuminuria (g/dL) was considered.
  5. eLow income was defined as < $20,000 and medium/high income was defined as ≥ $20,000.